IL11

Protein sy'n cael ei godio yn y corff dynol gan y genyn IL11 yw IL11 a elwir hefyd yn Interleukin 11 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19q13.42.

IL11
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4MHL
Dynodwyr
Cyfenwau	IL11, AGIF, IL-11, interleukin 11
Dynodwyr allanol	OMIM: 147681 HomoloGene: 535 GeneCards: IL11
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • growth factor activity • interleukin-11 receptor binding • cytokine activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • extracellular space • extracellular region Prosesau biolegol • negative regulation of endothelial cell apoptotic process • positive regulation of MAPK cascade • positive regulation of peptidyl-serine phosphorylation • B cell differentiation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • negative regulation of hormone secretion • positive regulation of peptidyl-tyrosine phosphorylation • fat cell differentiation • positive regulation of cell population proliferation • regulation of complement-dependent cytotoxicity • megakaryocyte differentiation • regulation of signaling receptor activity • cytokine-mediated signaling pathway • cardiovascular fibrosis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3589	n/a
Ensembl	ENSG00000095752	n/a
UniProt	P20809	n/a
RefSeq (mRNA)	NM_001267718 NM_000641	n/a
RefSeq (protein)	NP_000632 NP_001254647	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IL11.

• AGIF
• IL-11

Llyfryddiaeth

• "RhIL-11 treatment normalized Th1/Th2 and T-bet/GATA-3 imbalance in in human immune thrombocytopenic purpura (ITP). ". Int Immunopharmacol. 2016. PMID 27235596.
• "IL-11 in multiple sclerosis. ". Oncotarget. 2015. PMID 26452137.
• "Recombinant human interleukin-11 (IL-11) is a protective factor in severe sepsis with thrombocytopenia: A case-control study. ". Cytokine. 2015. PMID 26276375.
• "Emerging roles for IL-11 signaling in cancer development and progression: Focus on breast cancer. ". Cytokine Growth Factor Rev. 2015. PMID 26209885.
• "Genetic variants of IL-11 associated with risk of Hirschsprung disease.". Neurogastroenterol Motil. 2015. PMID 26172388.