IL15

Protein sy'n cael ei godio yn y corff dynol gan y genyn IL15 yw IL15 a elwir hefyd yn Interleukin 15 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q31.21.

IL15
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2XQB, 2Z3Q, 2Z3R, 4GS7
Dynodwyr
Cyfenwau	IL15, IL-15, interleukin 15
Dynodwyr allanol	OMIM: 600554 HomoloGene: 487 GeneCards: IL15
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • GO:0005145 cytokine receptor binding • cytokine activity Cydrannau o'r gell • cnewyllyn cell • integral component of plasma membrane • Golgi apparatus • endosome • nucleoplasm • bilen • cell surface • extracellular region • extracellular space • cytoplasm • cytosol • nuclear speck Prosesau biolegol • negative regulation of smooth muscle cell proliferation • cell maturation • extrathymic T cell selection • positive regulation of T cell proliferation • regulation of defense response to virus by host • positive regulation of inflammatory response • response to nutrient levels • positive regulation of protein O-linked glycosylation • positive regulation of interleukin-17 production • hyaluronan metabolic process • positive regulation of natural killer cell differentiation • regulation of T cell differentiation • positive regulation of tissue remodeling • cellular response to vitamin D • lymph node development • natural killer cell differentiation • positive regulation of natural killer cell proliferation • cell-cell signaling • skeletal muscle atrophy • GO:0072468 signal transduction • GO:0010260 heneiddio • NK T cell proliferation • positive regulation of immune response • inflammatory response • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • positive regulation of cell population proliferation • tyrosine phosphorylation of STAT protein • positive regulation of tyrosine phosphorylation of STAT protein • regulation of signaling receptor activity • interleukin-15-mediated signaling pathway • neutrophil activation • positive regulation of peptidyl-tyrosine phosphorylation • positive regulation of phagocytosis • negative regulation of cold-induced thermogenesis • macrophage differentiation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3600	n/a
Ensembl	ENSG00000164136	n/a
UniProt	P40933	n/a
RefSeq (mRNA)	NM_000585 NM_172174 NM_172175	n/a
RefSeq (protein)	NP_000576 NP_751915	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IL15.

• IL-15

Llyfryddiaeth

• "The IL15 +96522 A>T functional polymorphism is related to the differentiation of Th17 cells and the severity of Hashimoto's disease. ". Int J Immunogenet. 2017. PMID 28164472.
• "Interleukin-15 (IL-15) Strongly Correlates with Increasing HIV-1 Viremia and Markers of Inflammation. ". PLoS One. 2016. PMID 27880829.
• "Interleukin-15 enhances cytokine induced killer (CIK) cytotoxic potential against epithelial cancer cell lines via an innate pathway. ". Hum Immunol. 2016. PMID 27615504.
• "Interleukin-15 as a potential new target in Sjögren's syndrome-associated inflammation. ". Pathology. 2016. PMID 27567226.
• "The clinical significance and impact of interleukin 15 on keratinocyte cell growth and migration.". Int J Mol Med. 2016. PMID 27460304.