IRF2BPL

Protein sy'n cael ei godio yn y corff dynol gan y genyn IRF2BPL yw IRF2BPL a elwir hefyd yn Interferon regulatory factor 2 binding protein like (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q24.3.

IRF2BPL
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CS3
Dynodwyr
Cyfenwau	IRF2BPL, C14orf4, EAP1, interferon regulatory factor 2 binding protein like, enhanced at puberty protein 1, NEDAMSS
Dynodwyr allanol	OMIM: 611720 HomoloGene: 11555 GeneCards: IRF2BPL
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • molecular function • GO:0001948, GO:0016582 protein binding • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • transferase activity Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • extracellular space • ubiquitin ligase complex Prosesau biolegol • GO:1901227 negative regulation of transcription by RNA polymerase II • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • development of secondary female sexual characteristics • nervous system development • protein ubiquitination Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	64207	n/a
Ensembl	ENSG00000119669	n/a
UniProt	Q9H1B7	n/a
RefSeq (mRNA)	NM_024496	n/a
RefSeq (protein)	NP_078772	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IRF2BPL.

• EAP1
• C14orf4

Llyfryddiaeth

• "Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions. ". Pharmacogenomics. 2012. PMID 22379998.
• "Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1. ". J Biol Chem. 2002. PMID 12029088.
• "Characterization of C14orf4, a novel intronless human gene containing a polyglutamine repeat, mapped to the ARVD1 critical region. ". Biochem Biophys Res Commun. 2000. PMID 11095982.
• "Hypothalamic expression of Eap1 is not directly controlled by ovarian steroids. ". Endocrinology. 2009. PMID 19022886.
• "Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis.". J Clin Invest. 2007. PMID 17627301.