ITGB4

Protein sy'n cael ei godio yn y corff dynol gan y genyn ITGB4 yw ITGB4 a elwir hefyd yn Integrin beta-4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q25.1.

ITGB4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1QG3, 2YRZ, 3F7P, 3F7Q, 3F7R, 3FQ4, 3FSO, 3H6A, 4Q58, 4WTW, 4WTX
Dynodwyr
Cyfenwau	ITGB4, CD104, GP150, integrin subunit beta 4, JEB5A, JEB5B
Dynodwyr allanol	OMIM: 147557 HomoloGene: 179 GeneCards: ITGB4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • G protein-coupled receptor binding • neuregulin binding • insulin-like growth factor I binding • integrin binding Cydrannau o'r gell • integral component of membrane • bilen • receptor complex • Cellbilen • hemidesmosome • cell surface • integrin complex • cell junction • cell leading edge • extracellular exosome • cnewyllyn cell • focal adhesion Prosesau biolegol • hemidesmosome assembly • renal system development • nail development • cell motility • extracellular matrix organization • autophagy • cell communication • cell adhesion • response to wounding • mesodermal cell differentiation • integrin-mediated signaling pathway • digestive tract development • cell-matrix adhesion • skin development • amelogenesis • cell migration • cell adhesion mediated by integrin Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3691	n/a
Ensembl	ENSG00000132470	n/a
UniProt	P16144	n/a
RefSeq (mRNA)	NM_000213 NM_001005619 NM_001005731 NM_001321123	n/a
RefSeq (protein)	NP_000204 NP_001005619 NP_001005731 NP_001308052	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ITGB4.

• CD104
• GP150

Llyfryddiaeth

• "Pyloric atresia-junctional epidermolysis bullosa syndrome showing novel c.4505-4508insACTC mutations in integrin b4 gene (ITGB4). ". Turk J Pediatr. 2015. PMID 27186702.
• "The impact of intrinsic ageing on the protein composition of the dermal-epidermal junction. ". Mech Ageing Dev. 2016. PMID 27013376.
• "Identification of two rare and novel large deletions in ITGB4 gene causing epidermolysis bullosa with pyloric atresia. ". Exp Dermatol. 2016. PMID 26739954.
• "Role of Integrin β4 in Lung Endothelial Cell Inflammatory Responses to Mechanical Stress. ". Sci Rep. 2015. PMID 26572585.
• "Suppression of ITGB4 Gene Expression in PC-3 Cells with Short Interfering RNA Induces Changes in the Expression of β-Integrins Associated with RGD-Receptors.". Bull Exp Biol Med. 2015. PMID 26395630.