KDM5D

Protein sy'n cael ei godio yn y corff dynol gan y genyn KDM5D yw KDM5D a elwir hefyd yn Lysine demethylase 5D (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom Y dynol, band Yq11.223.

KDM5D
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2E6R, 2YQE
Dynodwyr
Cyfenwau	KDM5D, HY, HYA, JARID1D, SMCY, lysine demethylase 5D
Dynodwyr allanol	OMIM: 426000 HomoloGene: 55838 GeneCards: KDM5D
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • histone H3-methyl-lysine-4 demethylase activity • DNA binding • oxidoreductase activity • dioxygenase activity • metal ion binding • histone demethylase activity • androgen receptor binding • GO:0001948, GO:0016582 protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • chromatin binding • histone H3-tri/di/monomethyl-lysine-4 demethylase activity • methylated histone binding Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • fibrillar center • cydran cellog • histone methyltransferase complex Prosesau biolegol • histone H3-K4 demethylation • T cell antigen processing and presentation • transcription, DNA-templated • GO:0009373 regulation of transcription, DNA-templated • regulation of androgen receptor signaling pathway • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • GO:1901227 negative regulation of transcription by RNA polymerase II • histone H3-K4 demethylation, trimethyl-H3-K4-specific • chromatin remodeling Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8284	n/a
Ensembl	ENSG00000012817	n/a
UniProt	Q9BY66	n/a
RefSeq (mRNA)	NM_001146705 NM_001146706 NM_004653	n/a
RefSeq (protein)	NP_001140177 NP_001140178 NP_004644	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KDM5D.

• HY
• HYA
• SMCY
• JARID1D

Llyfryddiaeth

• "H-Y incompatibility predicts short-term outcomes for kidney transplant recipients. ". J Am Soc Nephrol. 2009. PMID 19541808.
• "Functional HY-specific CD8+ T cells are found in a high proportion of women following pregnancy with a male fetus. ". Biol Reprod. 2007. PMID 16988213.
• "JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis. ". Cancer Res. 2016. PMID 26747897.
• "Investigation of Histone Lysine-Specific Demethylase 5D KDM5D) Isoform Expression in Prostate Cancer Cell Lines: a System Approach. ". Iran Biomed J. 2016. PMID 26728332.
• "Two Splice Variants of Y Chromosome-Located Lysine-Specific Demethylase 5D Have Distinct Function in Prostate Cancer Cell Line (DU-145).". J Proteome Res. 2015. PMID 26215926.