LGALS9

Protein sy'n cael ei godio yn y corff dynol gan y genyn LGALS9 yw LGALS9 a elwir hefyd yn Galectin 9 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q11.2.

LGALS9
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2EAK, 2EAL, 2YY1, 2ZHK, 2ZHL, 2ZHM, 2ZHN, 3LSD, 3LSE, 3NV1, 3NV2, 3NV3, 3NV4, 3WLU, 3WV6
Dynodwyr
Cyfenwau	LGALS9, HUAT, LGALS9A, galectin 9
Dynodwyr allanol	OMIM: 601879 HomoloGene: 32078 GeneCards: LGALS9
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • galactose binding • signal transducer activity • enzyme binding • disaccharide binding • carbohydrate binding Cydrannau o'r gell • intracellular anatomical structure • extracellular region • extracellular exosome • cytoplasm • cnewyllyn cell • extracellular space • cytosol Prosesau biolegol • negative regulation of interferon-gamma production • response to interleukin-1 • toll-like receptor 4 signaling pathway • maternal process involved in female pregnancy • positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell • immune system process • positive regulation of CD4-positive, alpha-beta T cell proliferation • ERK1 and ERK2 cascade • female pregnancy • positive regulation of viral entry into host cell • positive regulation of monocyte chemotactic protein-1 production • natural killer cell tolerance induction • negative regulation of chemokine production • regulation of interleukin-5 production • toll-like receptor 2 signaling pathway • positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway • negative regulation of mast cell degranulation • negative regulation of gene expression • positive regulation of interleukin-4 production • chemotaxis • negative regulation of activated T cell proliferation • regulation of interleukin-4 production • response to lipopolysaccharide • GO:1901313 positive regulation of gene expression • positive regulation of NF-kappaB transcription factor activity • positive regulation of dendritic cell apoptotic process • positive regulation of ERK1 and ERK2 cascade • cellular response to interferon-gamma • positive regulation of I-kappaB kinase/NF-kappaB signaling • p38MAPK cascade • negative regulation of natural killer cell mediated cytotoxicity • positive regulation of transforming growth factor beta production • negative regulation of CD4-positive, alpha-beta T cell proliferation • positive regulation of dendritic cell differentiation • negative regulation of tumor necrosis factor production • positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response • inflammatory response • regulation of p38MAPK cascade • mature conventional dendritic cell differentiation • positive regulation of dendritic cell chemotaxis • positive regulation of activated T cell autonomous cell death Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3965	n/a
Ensembl	ENSG00000168961	n/a
UniProt	O00182	n/a
RefSeq (mRNA)	NM_002308 NM_009587 NM_001330163	n/a
RefSeq (protein)	NP_001317092 NP_002299 NP_033665	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LGALS9.

• HUAT
• LGALS9A

Llyfryddiaeth

• "Serum galectin-9 as a noninvasive biomarker for the detection of endometriosis and pelvic pain or infertility-related gynecologic disorders. ". Fertil Steril. 2017. PMID 29202955.
• "X-ray structure of a protease-resistant mutant form of human galectin-9 having two carbohydrate recognition domains with a metal-binding site. ". Biochem Biophys Res Commun. 2017. PMID 28687490.
• "Galectin-9 as a Predictive Marker for the Onset of Immune-Related Adverse Effects Associated with Anti-CCR4 MoAb Therapy in Patients with Adult T Cell Leukemia. ". Tohoku J Exp Med. 2017. PMID 28321034.
• "Cancer Therapy Due to Apoptosis: Galectin-9. ". Int J Mol Sci. 2017. PMID 28045432.
• "Galectin-9: From cell biology to complex disease dynamics.". J Biosci. 2016. PMID 27581941.