MDK

Protein sy'n cael ei godio yn y corff dynol gan y genyn MDK yw MDK a elwir hefyd yn Midkine (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11p11.2.

MDK
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1MKC, 1MKN
Dynodwyr
Cyfenwau	MDK, ARAP, MK, NEGF2, midkine (neurite growth-promoting factor 2), midkine
Dynodwyr allanol	OMIM: 162096 HomoloGene: 1792 GeneCards: MDK
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • growth factor activity • heparin binding Cydrannau o'r gell • cytoplasm • cell projection • extracellular region • collagen-containing extracellular matrix Prosesau biolegol • Notch signaling pathway • GO:1904089 negative regulation of neuron apoptotic process • regulation of behavior • cerebellar granular layer development • dentate gyrus development • response to glucocorticoid • behavioral fear response • nervous system development • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • multicellular organism development • defecation • short-term memory • cerebral cortex development • response to hormone • cell migration • hippocampus development • positive regulation of cell division • GO:0072468 signal transduction • negative regulation of neuron death • response to wounding • adrenal gland development • cell differentiation • regulation of signaling receptor activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4192	n/a
Ensembl	ENSG00000110492	n/a
UniProt	P21741	n/a
RefSeq (mRNA)	NM_001012333 NM_001012334 NM_001270550 NM_001270551 NM_001270552 NM_002391	n/a
RefSeq (protein)	NP_001012333 NP_001012334 NP_001257479 NP_001257480 NP_001257481 NP_002382	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MDK.

• MK
• ARAP
• NEGF2

Llyfryddiaeth

• "Diagnostic accuracy of ELISA for detecting serum Midkine in cancer patients. ". PLoS One. 2017. PMID 28686647.
• "Midkine is up-regulated in both cancerous and inflamed bowel, reflecting lymph node metastasis in colorectal cancer and clinical activity of ulcerative colitis. ". Cytokine. 2017. PMID 27692729.
• "Circulating midkine in children with Henoch-Schönlein purpura: Clinical implications. ". Int Immunopharmacol. 2016. PMID 27497193.
• "The role of midkine in the inflammatory process and its correlation with other inflammatory markers in renal transplant recipients. ". Int J Artif Organs. 2016. PMID 27470002.
• "Serum midkine as a biomarker for malignancy, prognosis, and chemosensitivity in head and neck squamous cell carcinoma.". Cancer Med. 2016. PMID 26798989.