NLGN4X

Protein sy'n cael ei godio yn y corff dynol gan y genyn NLGN4X yw NLGN4X a elwir hefyd yn Neuroligin 4, X-linked (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xp22.32-p22.31.

NLGN4X
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2WQZ, 2XB6, 3BE8
Dynodwyr
Cyfenwau	NLGN4X, ASPGX2, AUTSX2, HLNX, HNL4X, NLGN4, neuroligin 4, X-linked, neuroligin 4 X-linked
Dynodwyr allanol	OMIM: 300427 HomoloGene: 136297 GeneCards: NLGN4X
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • scaffold protein binding • GO:0004091 carboxylic ester hydrolase activity • neurexin family protein binding • GO:0001948, GO:0016582 protein binding • chloride ion binding • cell adhesion molecule binding • signaling receptor activity Cydrannau o'r gell • integral component of membrane • postsynaptic membrane • bilen • GO:0097483, GO:0097481 postsynaptic density • synapse • integral component of plasma membrane • excitatory synapse • cell surface • cell junction • dendrite • Cellbilen • intracellular anatomical structure • spanning component of membrane • presynapse • symmetric, GABA-ergic, inhibitory synapse • asymmetric, glutamatergic, excitatory synapse Prosesau biolegol • cell-cell junction organization • organ growth • neuron cell-cell adhesion • brainstem development • synapse organization • learning • cerebellum development • negative regulation of excitatory postsynaptic potential • presynaptic membrane assembly • vocalization behavior • adult behavior • cell adhesion • neuron differentiation • social behavior • synaptic vesicle endocytosis • postsynaptic membrane assembly • modulation of chemical synaptic transmission • presynapse assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	57502	n/a
Ensembl	ENSG00000146938	n/a
UniProt	Q8N0W4	n/a
RefSeq (mRNA)	NM_001282145 NM_001282146 NM_020742 NM_181332	n/a
RefSeq (protein)	NP_001269074 NP_001269075 NP_065793 NP_851849	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NLGN4X.

• HLNX
• HNL4X
• NLGN4
• ASPGX2
• AUTSX2

Llyfryddiaeth

• "Gender differences in cognitive ability associated with genetic variants of NLGN4. ". Neuropsychobiology. 2010. PMID 20714171.
• "A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export. ". J Neurosci. 2009. PMID 19726642.
• "Neuroligin 4X overexpression in human breast cancer is associated with poor relapse-free survival. ". PLoS One. 2017. PMID 29244827.
• "The functional genetic link of NLGN4X knockdown and neurodevelopment in neural stem cells. ". Hum Mol Genet. 2013. PMID 23710042.
• "Investigating synapse formation and function using human pluripotent stem cell-derived neurons.". Proc Natl Acad Sci U S A. 2011. PMID 21278334.