NSFL1C

Protein sy'n cael ei godio yn y corff dynol gan y genyn NSFL1C yw NSFL1C a elwir hefyd yn NSFL1 cofactor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20p13.

NSFL1C
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1SS6
Dynodwyr
Cyfenwau	NSFL1C, P47, UBX1, UBXD10, UBXN2C, dJ776F14.1, NSFL1 cofactor
Dynodwyr allanol	OMIM: 606610 HomoloGene: 41114 GeneCards: NSFL1C
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • lipid binding • ubiquitin binding • GO:0001948, GO:0016582 protein binding • phospholipid binding • protein phosphatase regulator activity • ATPase binding Cydrannau o'r gell • Golgi stack • Cellbilen • Golgi apparatus • intermediate filament cytoskeleton • VCP-NSFL1C complex • cnewyllyn cell • nucleoplasm • Cromosom • cytosol • spindle pole centrosome • cytoplasm • microtubule organizing center • Cytosgerbwd Prosesau biolegol • membrane fusion • nuclear membrane reassembly • Golgi organization • proteasome-mediated ubiquitin-dependent protein catabolic process • autophagosome assembly • regulation of phosphoprotein phosphatase activity • establishment of mitotic spindle orientation • positive regulation of mitotic centrosome separation • negative regulation of protein localization to centrosome Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	55968	n/a
Ensembl	ENSG00000088833	n/a
UniProt	Q9UNZ2	n/a
RefSeq (mRNA)	NM_001206736 NM_016143 NM_018839 NM_182483	n/a
RefSeq (protein)	NP_001193665 NP_057227 NP_061327	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NSFL1C.

• P47
• UBX1
• UBXD10
• UBXN2C
• dJ776F14.1

Llyfryddiaeth

• "The opposite role of two UBA-UBX containing proteins, p47 and SAKS1 in the degradation of a single ERAD substrate, α-TCR. ". Mol Cell Biochem. 2017. PMID 27785701.
• "Characterization of an Additional Binding Surface on the p97 N-Terminal Domain Involved in Bipartite Cofactor Interactions. ". Structure. 2016. PMID 26712280.
• "Altered cofactor regulation with disease-associated p97/VCP mutations. ". Proc Natl Acad Sci U S A. 2015. PMID 25775548.
• "Brain-derived neurotrophic factor promotes angiogenic tube formation through generation of oxidative stress in human vascular endothelial cells. ". Acta Physiol (Oxf). 2014. PMID 24612679.
• "p47 is a cofactor for p97-mediated membrane fusion.". Nature. 1997. PMID 9214505.