NUDT4

Protein sy'n cael ei godio yn y corff dynol gan y genyn NUDT4 yw NUDT4 a elwir hefyd yn Diphosphoinositol polyphosphate phosphohydrolase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q22.

NUDT4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DUK
Dynodwyr
Cyfenwau	NUDT4, DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, nudix hydrolase 4, DIPP-2B, NUDT4B
Dynodwyr allanol	OMIM: 609229 HomoloGene: 41726 GeneCards: NUDT4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • inositol diphosphate tetrakisphosphate diphosphatase activity • inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity • inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity • inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity • metal ion binding • GO:0001948, GO:0016582 protein binding • RNA binding • inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity • hydrolase activity • diphosphoinositol-polyphosphate diphosphatase activity • inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity • inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity • inositol diphosphate pentakisphosphate diphosphatase activity • inositol bisdiphosphate tetrakisphosphate diphosphatase activity • endopolyphosphatase activity • bis(5'-adenosyl)-hexaphosphatase activity • bis(5'-adenosyl)-pentaphosphatase activity • m7G(5')pppN diphosphatase activity • snoRNA binding Cydrannau o'r gell • intracellular anatomical structure • cnewyllyn cell • cytoplasm • cytosol Prosesau biolegol • GO:0007243 intracellular signal transduction • cyclic nucleotide metabolic process • inositol phosphate metabolic process • cyclic-nucleotide-mediated signaling • calcium-mediated signaling • diphosphoinositol polyphosphate metabolic process • diadenosine pentaphosphate catabolic process • diadenosine hexaphosphate catabolic process • adenosine 5'-(hexahydrogen pentaphosphate) catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	11163	n/a
Ensembl	ENSG00000173598	n/a
UniProt	Q9NZJ9	n/a
RefSeq (mRNA)	NM_001301022 NM_001301023 NM_001301024 NM_019094 NM_199040	n/a
RefSeq (protein)	NP_001287951 NP_001287952 NP_001287953 NP_061967 NP_950241	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NUDT4.

• DIPP2
• HDCMB47P
• DIPP2beta
• DIPP2alpha

Llyfryddiaeth

• "Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate. ". J Biol Chem. 2002. PMID 12370170.
• "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. ". DNA Res. 1997. PMID 9455484.
• "Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. An expanding Nudt family. ". J Biol Chem. 2000. PMID 10777568.
• "Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases. ". BMC Biochem. 2002. PMID 12121577.
• "Genetic rationale for microheterogeneity of human diphosphoinositol polyphosphate phosphohydrolase type 2.". Gene. 2001. PMID 11376937.