PACSIN2

Protein sy'n cael ei godio yn y corff dynol gan y genyn PACSIN2 yw PACSIN2 a elwir hefyd yn Protein kinase C and casein kinase substrate in neurons 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q13.2.

PACSIN2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3ABH, 3ACO, 3HAJ, 3Q0K
Dynodwyr
Cyfenwau	PACSIN2, SDPII, protein kinase C and casein kinase substrate in neurons 2
Dynodwyr allanol	OMIM: 604960 HomoloGene: 21414 GeneCards: PACSIN2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transporter activity • cytoskeletal protein binding • phosphatidic acid binding • GO:0001948, GO:0016582 protein binding • identical protein binding • lipid binding • cadherin binding • phospholipid binding Cydrannau o'r gell • endosome • cell projection • bilen • intracellular membrane-bounded organelle • cell-cell junction • focal adhesion • ruffle membrane • recycling endosome membrane • early endosome • caveola • extracellular exosome • cytoplasmic vesicle membrane • Cytosgerbwd • GO:0016023 cytoplasmic vesicle • extrinsic component of membrane • cytoplasm • cytosol • Cellbilen • nuclear speck • glutamatergic synapse Prosesau biolegol • regulation of endocytosis • caveolin-mediated endocytosis • negative regulation of endocytosis • endocytosis • caveola assembly • plasma membrane tubulation • protein localization to endosome • cell projection morphogenesis • actin cytoskeleton organization • membrane organization • cytoskeleton organization • modulation of chemical synaptic transmission Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	11252	n/a
Ensembl	ENSG00000100266	n/a
UniProt	Q9UNF0	n/a
RefSeq (mRNA)	NM_001184970 NM_001184971 NM_007229 NM_001349968 NM_001349969 NM_001349970 NM_001349971 NM_001349972 NM_001349973 NM_001349974	n/a
RefSeq (protein)	NP_001171899 NP_001171900 NP_009160 NP_001336897 NP_001336898 NP_001336899 NP_001336900 NP_001336901 NP_001336902 NP_001336903	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PACSIN2.

• SDPII

Llyfryddiaeth

• "FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets. ". Blood. 2015. PMID 25838348.
• "The F-BAR protein PACSIN2 regulates epidermal growth factor receptor internalization. ". J Biol Chem. 2012. PMID 23129763.
• "Tip-to-tip interaction in the crystal packing of PACSIN 2 is important in regulating tubulation activity. ". Protein Cell. 2013. PMID 23888307.
• "Clostridium difficile Toxin A Undergoes Clathrin-Independent, PACSIN2-Dependent Endocytosis. ". PLoS Pathog. 2016. PMID 27942025.
• "Phosphorylation of PACSIN2 by protein kinase C triggers the removal of caveolae from the plasma membrane.". J Cell Sci. 2015. PMID 26092940.