PATZ1

Protein sy'n cael ei godio yn y corff dynol gan y genyn PATZ1 yw PATZ1 a elwir hefyd yn POZ/BTB and AT hook containing zinc finger 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q12.2.

PATZ1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2EPP, 2EPQ, 2EPR, 2EPS, 2YT9
Dynodwyr
Cyfenwau	PATZ1, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG, dJ400N23, POZ/BTB and AT hook containing zinc finger 1
Dynodwyr allanol	OMIM: 605165 HomoloGene: 8636 GeneCards: PATZ1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • chromatin binding • GO:0001948, GO:0016582 protein binding • metal ion binding • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell • nucleoplasm Prosesau biolegol • regulation of gene expression • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • T cell differentiation • male gonad development • GO:0045996 negative regulation of transcription, DNA-templated • GO:0009373 regulation of transcription, DNA-templated • transcription by RNA polymerase II • spermatogenesis • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23598	n/a
Ensembl	ENSG00000100105	n/a
UniProt	Q9HBE1	n/a
RefSeq (mRNA)	NM_032052 NM_014323 NM_032050 NM_032051	n/a
RefSeq (protein)	NP_055138 NP_114439 NP_114440 NP_114441	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PATZ1.

• ZSG
• MAZR
• PATZ
• RIAZ
• ZBTB19
• ZNF278
• dJ400N23

Llyfryddiaeth

• "Zinc finger protein 278, a potential oncogene in human colorectal cancer. ". Acta Biochim Biophys Sin (Shanghai). 2008. PMID 18401526.
• "PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c. ". Nucleic Acids Res. 2017. PMID 27932482.
• "PATZ1 acts as a tumor suppressor in thyroid cancer via targeting p53-dependent genes involved in EMT and cell migration. ". Oncotarget. 2015. PMID 25595894.
• "Patz1 regulates embryonic stem cell identity. ". Stem Cells Dev. 2014. PMID 24380431.
• "[Association of single nucleotide polymorphisms of PATZ1 gene with azoospermia].". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2010. PMID 20677143.