PFKFB1

Protein sy'n cael ei godio yn y corff dynol gan y genyn PFKFB1 yw PFKFB1 a elwir hefyd yn 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xp11.21.

PFKFB1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1K6M
Dynodwyr
Cyfenwau	PFKFB1, F6PK, HL2K, PFRX, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Dynodwyr allanol	OMIM: 311790 HomoloGene: 105654 GeneCards: PFKFB1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • fructose-6-phosphate binding • kinase activity • catalytic activity • GO:0001948, GO:0016582 protein binding • identical protein binding • fructose-2,6-bisphosphate 2-phosphatase activity • hydrolase activity • ATP binding • 6-phosphofructo-2-kinase activity • kinase binding Cydrannau o'r gell • cytosol • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex Prosesau biolegol • gluconeogenesis • response to glucagon • glycolytic process • phosphorylation • fructose metabolic process • response to glucocorticoid • carbohydrate phosphorylation • response to insulin • positive regulation of glucokinase activity • fructose 2,6-bisphosphate metabolic process • animal organ regeneration • response to starvation • metabolaeth • response to cAMP • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • negative regulation of glycolytic process • positive regulation of glycolytic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5207	n/a
Ensembl	ENSG00000158571	n/a
UniProt	P16118	n/a
RefSeq (mRNA)	NM_001271804 NM_001271805 NM_002625	n/a
RefSeq (protein)	NP_001258733 NP_001258734 NP_002616	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PFKFB1.

• F6PK
• HL2K
• PFRX

Llyfryddiaeth

• "Tissue-specific structure/function differentiation of the liver isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. ". J Biol Chem. 2003. PMID 12379646.
• "cDNA sequence and kinetic properties of human lung fructose(1, 6)bisphosphatase. ". Arch Biochem Biophys. 1999. PMID 10222032.
• "Localization of human liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB1) within a YAC contig in Xp11.21. ". Genomics. 1997. PMID 9119406.
• "Glucocorticoid regulation of hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene expression. ". J Biol Chem. 1989. PMID 2540168.
• "Sequence of human liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.". Nucleic Acids Res. 1990. PMID 2163524.