PIK3R3

Protein sy'n cael ei godio yn y corff dynol gan y genyn PIK3R3 yw PIK3R3 a elwir hefyd yn Phosphoinositide-3-kinase regulatory subunit 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p34.1.

PIK3R3
Dynodwyr
Cyfenwau	PIK3R3, p55, p55-GAMMA, p55PIK, phosphoinositide-3-kinase regulatory subunit 3, PI3KR3
Dynodwyr allanol	OMIM: 606076 HomoloGene: 2690 GeneCards: PIK3R3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phosphatidylinositol 3-kinase regulator activity • GO:0001948, GO:0016582 protein binding • 1-phosphatidylinositol-3-kinase activity • phosphotyrosine residue binding • 1-phosphatidylinositol-3-kinase regulator activity Cydrannau o'r gell • cytosol • phosphatidylinositol 3-kinase complex Prosesau biolegol • regulation of phosphatidylinositol 3-kinase activity • phosphatidylinositol-3-phosphate biosynthetic process • GO:1901047 insulin receptor signaling pathway • positive regulation of protein phosphorylation • cell migration involved in sprouting angiogenesis • GO:1901313 positive regulation of gene expression • protein kinase B signaling • positive regulation of cell migration • phosphatidylinositol phosphate biosynthetic process • phosphatidylinositol biosynthetic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8503	n/a
Ensembl	ENSG00000117461	n/a
UniProt	Q92569	n/a
RefSeq (mRNA)	NM_001114172 NM_001303428 NM_001303429 NM_001328648 NM_001328649 NM_001328650 NM_001328651 NM_001328652 NM_001328653 NM_001328654 NM_003629	n/a
RefSeq (protein)	NP_001107644 NP_001290357 NP_001290358 NP_001315577 NP_001315578 NP_001315579 NP_001315580 NP_001315581 NP_001315582 NP_001315583 NP_003620	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PIK3R3.

• p55
• p55PIK
• p55-GAMMA

Llyfryddiaeth

• "Blocking p55PIK signaling inhibits proliferation and induces differentiation of leukemia cells. ". Cell Death Differ. 2012. PMID 22722333.
• "p55PIK regulates alpha-fetoprotein expression through the NF-κB signaling pathway. ". Life Sci. 2017. PMID 28970114.
• "Changes in phosphatidylinositol 3-kinase 55 kDa gamma expression and subcellular localization may be caspase 6 dependent in paraquat-induced SH-SY5Y apoptosis. ". Hum Exp Toxicol. 2014. PMID 24130211.
• "Effects of the 24 N-terminal amino acids of p55PIK on endotoxinstimulated release of inflammatory cytokines by HaCaT cells. ". J Huazhong Univ Sci Technolog Med Sci. 2013. PMID 23904382.
• "Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library.". BMC Med Genomics. 2012. PMID 22876838.