PLCD1

Protein sy'n cael ei godio yn y corff dynol gan y genyn PLCD1 yw PLCD1 a elwir hefyd yn Phospholipase C delta 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3p22.2.

PLCD1
Dynodwyr
Cyfenwau	PLCD1, NDNC3, PLC-III, phospholipase C delta 1
Dynodwyr allanol	OMIM: 602142 HomoloGene: 21252 GeneCards: PLCD1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GTPase activating protein binding • calcium ion binding • phosphatidylinositol phosphate binding • phosphatidylserine binding • signal transducer activity • metal ion binding • phosphatidic acid binding • phosphoric diester hydrolase activity • phospholipase C activity • hydrolase activity • phosphatidylinositol phospholipase C activity • phosphatidylinositol-4,5-bisphosphate binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • cytosol • Cellbilen • extracellular exosome Prosesau biolegol • GO:0007243 intracellular signal transduction • lipid metabolism • labyrinthine layer blood vessel development • inositol phosphate metabolic process • lipid catabolic process • regulation of cell population proliferation • angiogenesis • phospholipid metabolic process • GO:0072468 signal transduction • inositol trisphosphate biosynthetic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5333	n/a
Ensembl	ENSG00000187091	n/a
UniProt	P51178	n/a
RefSeq (mRNA)	NM_001130964 NM_006225	n/a
RefSeq (protein)	NP_001124436 NP_006216	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PLCD1.

• NDNC3
• PLC-III

Llyfryddiaeth

• "Mutations in the gene phospholipase C, delta-1 (PLCD1) underlying hereditary leukonychia. ". Eur J Dermatol. 2012. PMID 23149345.
• "Epigenetic inactivation of PLCD1 in chronic myeloid leukemia. ". Int J Mol Med. 2012. PMID 22576628.
• "Phospholipase C δ1 negatively regulates autophagy in colorectal cancer cells. ". Biochem Biophys Res Commun. 2017. PMID 28528980.
• "Methylation of PLCD1 and adenovirus-mediated PLCD1 overexpression elicits a gene therapy effect on human breast cancer. ". Exp Cell Res. 2015. PMID 25655282.
• "Intramolecular allosteric interaction in the phospholipase C-δ1 pleckstrin homology domain.". Biochim Biophys Acta. 2013. PMID 23388389.