PPBP

Protein sy'n cael ei godio yn y corff dynol gan y genyn PPBP yw PPBP a elwir hefyd yn Pro-platelet basic protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q13.3.

PPBP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1TVX, 1F9P, 1NAP
Dynodwyr
Cyfenwau	PPBP, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, pro-platelet basic protein
Dynodwyr allanol	OMIM: 121010 HomoloGene: 136759 GeneCards: PPBP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • growth factor activity • cytokine activity • glucose transmembrane transporter activity • CXCR chemokine receptor binding • chemokine activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • platelet alpha granule lumen • extracellular region • extracellular space • tertiary granule lumen • platelet alpha granule Prosesau biolegol • response to lipopolysaccharide • regulation of cell population proliferation • chemotaxis • positive regulation of cell division • platelet degranulation • defense response to bacterium • inflammatory response • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • chemokine-mediated signaling pathway • defense response • positive regulation of neutrophil chemotaxis • antimicrobial humoral immune response mediated by antimicrobial peptide • regulation of signaling receptor activity • neutrophil degranulation • cell chemotaxis • G protein-coupled receptor signaling pathway • glucose transmembrane transport • neutrophil chemotaxis • leukocyte chemotaxis • cellular response to lipopolysaccharide Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5473	n/a
Ensembl	ENSG00000163736	n/a
UniProt	P02775	n/a
RefSeq (mRNA)	NM_002704	n/a
RefSeq (protein)	NP_002695	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PPBP.

• PBP
• TC1
• TC2
• TGB
• LDGF
• MDGF
• TGB1
• B-TG1
• CTAP3
• CXCL7
• NAP-2
• SCYB7
• THBGB
• LA-PF4
• THBGB1
• Beta-TG
• CTAPIII
• CTAP-III

Llyfryddiaeth

• "Expression level of CXCL7 in peripheral blood cells is a potential biomarker for the diagnosis of renal cell carcinoma. ". Cancer Sci. 2017. PMID 28985012.
• "Chemokine CXCL7 Heterodimers: Structural Insights, CXCR2 Receptor Function, and Glycosaminoglycan Interactions. ". Int J Mol Sci. 2017. PMID 28368308.
• "CXCL7 promotes proliferation and invasion of cholangiocarcinoma cells. ". Oncol Rep. 2017. PMID 27959418.
• "Novel TIA biomarkers identified by mass spectrometry-based proteomics. ". Int J Stroke. 2015. PMID 26307429.
• "Dynamics and thermodynamic properties of CXCL7 chemokine.". Proteins. 2015. PMID 26297927.