PPIE

Protein sy'n cael ei godio yn y corff dynol gan y genyn PPIE yw PPIE a elwir hefyd yn Peptidyl-prolyl cis-trans isomerase E a Peptidylprolyl isomerase E (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p34.2.

PPIE
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ZMF, 2CQB, 2KU7, 2KYX, 2R99, 3LPY, 3MDF, 3UCH
Dynodwyr
Cyfenwau	PPIE, CYP-33, CYP33, peptidylprolyl isomerase E
Dynodwyr allanol	OMIM: 602435 HomoloGene: 38142 GeneCards: PPIE
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • isomerase activity • peptidyl-prolyl cis-trans isomerase activity • GO:0001948, GO:0016582 protein binding • nucleic acid binding • cyclosporin A binding • RNA binding • mRNA binding • poly(A) binding • unfolded protein binding Cydrannau o'r gell • catalytic step 2 spliceosome • nucleoplasm • spliceosomal complex • cnewyllyn cell • extracellular region • cytosol • nuclear speck • secretory granule lumen • ficolin-1-rich granule lumen • U2-type catalytic step 2 spliceosome Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • mRNA processing • protein peptidyl-prolyl isomerization • protein folding • RNA splicing • positive regulation of viral genome replication • transcription-coupled nucleotide-excision repair • mRNA splicing, via spliceosome • neutrophil degranulation • protein refolding Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10450	n/a
Ensembl	ENSG00000084072	n/a
UniProt	Q9UNP9	n/a
RefSeq (mRNA)	NM_001195007 NM_006112 NM_203456 NM_203457 NM_001319293	n/a
RefSeq (protein)	NP_001181936 NP_001306222 NP_006103 NP_982281	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PPIE.

• CYP33
• CYP-33

Llyfryddiaeth

• "Co-amplification of a novel cyclophilin-like gene (PPIE) with L-myc in small cell lung cancer cell lines. ". Oncogene. 1998. PMID 9747881.
• "A nuclear RNA-binding cyclophilin in human T cells. ". FEBS Lett. 1996. PMID 8977107.
• "Cyclophilin E functions as a negative regulator to influenza virus replication by impairing the formation of the viral ribonucleoprotein complex. ". PLoS One. 2011. PMID 21887220.
• "Human CyP33 binds specifically to mRNA and binding stimulates PPIase activity of hCyP33. ". FEBS Lett. 2008. PMID 18258190.
• "1.88 A crystal structure of the C domain of hCyP33: a novel domain of peptidyl-prolyl cis-trans isomerase.". Biochem Biophys Res Commun. 2005. PMID 15963461.