PPIL2

Protein sy'n cael ei godio yn y corff dynol gan y genyn PPIL2 yw PPIL2 a elwir hefyd yn Peptidylprolyl isomerase like 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 22, band 22q11.21.

PPIL2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ZKC
Dynodwyr
Cyfenwau	PPIL2, CYC4, CYP60, Cyp-60, UBOX7, hCyP-60, peptidylprolyl isomerase like 2
Dynodwyr allanol	OMIM: 607588 HomoloGene: 8643 GeneCards: PPIL2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • ubiquitin-ubiquitin ligase activity • GO:0001948, GO:0016582 protein binding • isomerase activity • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • GO:0050372 ubiquitin-protein transferase activity • transferase activity • peptidyl-prolyl cis-trans isomerase activity • cyclosporin A binding Cydrannau o'r gell • cytoplasm • Golgi lumen • Cellbilen • cnewyllyn cell • nucleoplasm Prosesau biolegol • protein polyubiquitination • protein localization to plasma membrane • protein folding • protein ubiquitination • leukocyte migration • protein peptidyl-prolyl isomerization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23759	n/a
Ensembl	ENSG00000100023	n/a
UniProt	Q13356	n/a
RefSeq (mRNA)	NM_014337 NM_148175 NM_148176 NM_001317996	n/a
RefSeq (protein)	NP_001304925 NP_055152 NP_680480 NP_680481	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PPIL2.

• CYC4
• CYP60
• UBOX7
• Cyp-60
• hCyP-60

Llyfryddiaeth

• "U box proteins as a new family of ubiquitin-protein ligases. ". J Biol Chem. 2001. PMID 11435423.
• "Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperones. ". Genes Cells. 2004. PMID 15189447.
• "Identification of a nuclear-specific cyclophilin which interacts with the proteinase inhibitor eglin c. ". Biochem J. 1996. PMID 8660300.
• "Variation in RTN3 and PPIL2 genes does not influence platelet membrane beta-secretase activity or susceptibility to alzheimer's disease in the northern Irish population. ". Neuromolecular Med. 2009. PMID 19669607.
• "Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60.". J Biol Chem. 2005. PMID 15946952.