PRKAB2

Protein sy'n cael ei godio yn y corff dynol gan y genyn PRKAB2 yw PRKAB2 a elwir hefyd yn Protein kinase AMP-activated non-catalytic subunit beta 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q21.1.

PRKAB2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2F15, 2V8Q, 2V92, 2V9J, 2Y8L, 2Y8Q, 2YA3, 4CFH, 4EAI, 4EAJ, 4RER, 4REW
Dynodwyr
Cyfenwau	PRKAB2, protein kinase AMP-activated non-catalytic subunit beta 2
Dynodwyr allanol	OMIM: 602741 HomoloGene: 38046 GeneCards: PRKAB2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • AMP-activated protein kinase activity • GO:0001948, GO:0016582 protein binding • identical protein binding • protein kinase binding Cydrannau o'r gell • cytosol • nucleoplasm • nucleotide-activated protein kinase complex • cnewyllyn cell • cytoplasm Prosesau biolegol • lipid metabolism • regulation of fatty acid biosynthetic process • fatty acid metabolic process • fatty acid biosynthetic process • macroautophagy • protein phosphorylation • GO:0072468 signal transduction • GO:0048552 regulation of catalytic activity • positive regulation of cold-induced thermogenesis • carnitine shuttle • regulation of macroautophagy • regulation of signal transduction by p53 class mediator Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5565	n/a
Ensembl	ENSG00000131791	n/a
UniProt	O43741	n/a
RefSeq (mRNA)	NM_005399	n/a
RefSeq (protein)	NP_005390	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Llyfryddiaeth

• "Effects of thyroid state on AMP-activated protein kinase and acetyl-CoA carboxylase expression in muscle. ". J Appl Physiol (1985). 2002. PMID 12433937.
• "Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle. ". J Biol Chem. 1998. PMID 9575201.
• "Variant screening of PRKAB2, a type 2 diabetes mellitus susceptibility candidate gene on 1q in Pima Indians. ". Mol Cell Probes. 2002. PMID 12490143.
• "Sumoylation of AMPKβ2 subunit enhances AMP-activated protein kinase activity. ". Mol Biol Cell. 2013. PMID 23552691.
• "Association study between variants of AMP-activated protein kinase catalytic and regulatory subunit genes with antipsychotic-induced weight gain.". J Psychiatr Res. 2012. PMID 22305490.