PTGS1

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTGS1 yw PTGS1 a elwir hefyd yn Prostaglandin-endoperoxide synthase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q33.2.

PTGS1
Dynodwyr
Cyfenwau	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS, prostaglandin-endoperoxide synthase 1
Dynodwyr allanol	OMIM: 176805 HomoloGene: 743 GeneCards: PTGS1
EC number	1.14.99.1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • oxidoreductase activity • prostaglandin-endoperoxide synthase activity • dioxygenase activity • heme binding • metal ion binding • peroxidase activity Cydrannau o'r gell • cnewyllyn cell • intracellular membrane-bounded organelle • photoreceptor outer segment • organelle membrane • extracellular exosome • bilen • Reticwlwm endoplasmig • cytoplasm • Golgi apparatus • endoplasmic reticulum membrane Prosesau biolegol • prostaglandin biosynthetic process • fatty acid biosynthetic process • GO:0001306 response to oxidative stress • regulation of cell population proliferation • prostaglandin metabolic process • regulation of blood pressure • cyclooxygenase pathway • lipid metabolism • inflammatory response • xenobiotic metabolic process • fatty acid metabolic process • cellular oxidant detoxification Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5742	n/a
Ensembl	ENSG00000095303	n/a
UniProt	P23219	n/a
RefSeq (mRNA)	NM_000962 NM_001271164 NM_001271165 NM_001271166 NM_001271367 NM_001271368 NM_080591	n/a
RefSeq (protein)	NP_000953 NP_001258093 NP_001258094 NP_001258095 NP_001258296 NP_001258297 NP_542158	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTGS1.

• COX1
• COX3
• PHS1
• PCOX1
• PES-1
• PGHS1
• PTGHS
• PGG/HS
• PGHS-1

Llyfryddiaeth

• "Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A3, a Neutrophil-activating Eicosanoid. ". J Biol Chem. 2016. PMID 27129261.
• "Origin of the Enigmatic Stepwise Tight-Binding Inhibition of Cyclooxygenase-1. ". Biochemistry. 2015. PMID 26562384.
• "Epithelial Cells Induce a Cyclo-Oxygenase-1-Dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype. ". Am J Respir Cell Mol Biol. 2017. PMID 28708434.
• "Colonic Saturated Fatty Acid Concentrations and Expression of COX-1, but not Diet, Predict Prostaglandin E2 in Normal Human Colon Tissue. ". Nutr Cancer. 2016. PMID 27548026.
• "Does COX1 gene polymorphism (A842G/C50T) influence peptic ulcer bleeding in Indian patients?.". Trop Gastroenterol. 2015. PMID 27522738.