PTPRF

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTPRF yw PTPRF a elwir hefyd yn Protein tyrosine phosphatase, receptor type F (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p34.2.

PTPRF
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1LAR, 2DJU, 2EDX, 2EDY, 2YD5, 2YD8, 4N5U, 2DN7
Dynodwyr
Cyfenwau	PTPRF, LAR, BNAH2, protein tyrosine phosphatase, receptor type F, protein tyrosine phosphatase receptor type F
Dynodwyr allanol	OMIM: 179590 HomoloGene: 20623 GeneCards: PTPRF
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • chondroitin sulfate proteoglycan binding • heparin binding • phosphoprotein phosphatase activity • GO:0098519, GO:0098518 phosphatase activity • GO:0032403 protein-containing complex binding • protein tyrosine phosphatase activity • transmembrane receptor protein tyrosine phosphatase activity • hydrolase activity • cell adhesion molecule binding Cydrannau o'r gell • integral component of membrane • bilen • integral component of plasma membrane • neuronal cell body • neuron projection • extracellular exosome • Cellbilen Prosesau biolegol • neuron projection regeneration • regulation of axon regeneration • negative regulation of receptor binding • regulation of neuron projection development • GO:0016576 protein dephosphorylation • transmembrane receptor protein tyrosine phosphatase signaling pathway • cell adhesion • peptidyl-tyrosine dephosphorylation • cell migration • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • synaptic membrane adhesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5792	n/a
Ensembl	ENSG00000142949	n/a
UniProt	P10586	n/a
RefSeq (mRNA)	NM_002840 NM_130440 NM_001329137 NM_001329138 NM_001329139 NM_001329140	n/a
RefSeq (protein)	NP_001316066 NP_001316067 NP_001316068 NP_001316069 NP_002831 NP_569707	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTPRF.

• LAR
• BNAH2

Llyfryddiaeth

• "Knock-down of LAR protein tyrosine phosphatase induces insulin resistance. ". FEBS Lett. 2005. PMID 15896785.
• "Protein tyrosine phosphatases as negative regulators of mitogenic signaling. ". J Cell Physiol. 1999. PMID 10395287.
• "PTPRF Expression as a Potential Prognostic/Predictive Marker for Treatment with Erlotinib in Non-Small-Cell Lung Cancer. ". J Thorac Oncol. 2015. PMID 26291013.
• "Homozygous truncating PTPRF mutation causes athelia. ". Hum Genet. 2014. PMID 24781087.
• "Functional genomics identified a novel protein tyrosine phosphatase receptor type F-mediated growth inhibition in hepatocarcinogenesis.". Hepatology. 2014. PMID 24470239.