RAB11A

RAB11A
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1OIV, 1OIW, 1OIX, 1YZK, 2D7C, 2GZD, 2GZH, 2HV8, 4C4P, 4D0L, 4D0M, 4LWZ, 4LX0, 4UJ3, 4UJ4, 4UJ5, 5C4G, 5C46, 5EUQ
Dynodwyr
Cyfenwau	RAB11A, YL8, member RAS oncogene family
Dynodwyr allanol	OMIM: 605570 HomoloGene: 37903 GeneCards: RAB11A
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • GTP binding; • myosin V binding; • GO:0006184 GTPase activity; • microtubule binding; • syntaxin binding; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• extracellular exosome; • transport vesicle; • cytoplasm; • mitocondria; • multivesicular body; • trans-Golgi network; • Golgi apparatus; • cytosol; • kinetochore microtubule; • axon; • spindle pole; • bilen; • centrosome; • perinuclear region of cytoplasm; • Cellbilen; • cleavage furrow; • cytoplasmic vesicle membrane; • GO:0016023 cytoplasmic vesicle; • fesigl; • endosome; • phagocytic vesicle; • recycling endosome; • recycling endosome membrane; • postsynaptic recycling endosome; • microtubule organizing center; • GO:0009327 protein-containing complex; • intracellular membrane-bounded organelle; • Schaffer collateral - CA1 synapse; • glutamatergic synapse; • intracellular anatomical structure;
Prosesau biolegol	• regulation of vesicle-mediated transport; • positive regulation of G2/M transition of mitotic cell cycle; • multivesicular body assembly; • cell cycle; • astral microtubule organization; • regulation of long-term neuronal synaptic plasticity; • establishment of protein localization to membrane; • cytokinesis; • positive regulation of axon extension; • establishment of vesicle localization; • renal water homeostasis; • regulation of multivesicular body size; • establishment of protein localization to organelle; • neuron projection development; • protein localization to plasma membrane; • plasma membrane to endosome transport; • mitotic spindle assembly; • regulation of protein transport; • protein transport; • mitotic metaphase plate congression; • exosomal secretion; • vesicle-mediated transport; • positive regulation of epithelial cell migration; • melanosome transport; • ciliary basal body-plasma membrane docking; • positive regulation of protein localization to plasma membrane; • neurotransmitter receptor transport, endosome to postsynaptic membrane; • post-translational protein modification; • GO:0015915 transport; • intracellular protein transport; • exocytosis; • regulation of cytokinesis; • Rab protein signal transduction; • vesicle-mediated transport in synapse; • amyloid-beta clearance by transcytosis; • small GTPase mediated signal transduction;
	Sources:Amigo / QuickGO
Orthologau
	8766
	n/a
	ENSG00000103769
	n/a
	P62491
	n/a
	NM_004663; NM_001206836
	n/a
	NP_001193765; NP_004654
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB11A yw RAB11A a elwir hefyd yn Ras-related protein Rab-11A a RAB11A, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q22.31.^[2]

Cyfystyron golygu

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAB11A.

YL8

Llyfryddiaeth golygu

"Mumps Virus Is Released from the Apical Surface of Polarized Epithelial Cells, and the Release Is Facilitated by a Rab11-Mediated Transport System. ". J Virol. 2015. PMID 26378159.
"Shigella subverts the host recycling compartment to rupture its vacuole. ". Cell Host Microbe. 2014. PMID 25299335.
"Intracellular Colocalization of Influenza Viral RNA and Rab11A Is Dependent upon Microtubule Filaments. ". J Virol. 2017. PMID 28724771.
"Rab11 collaborates E-cadherin to promote collective cell migration and indicates a poor prognosis in colorectal carcinoma. ". Eur J Clin Invest. 2016. PMID 27696383.
"Molecular mechanism of constitutively active Rab11A was revealed by crystal structure of Rab11A S20V.". FEBS Lett. 2016. PMID 26879265.

Cyfeiriadau golygu

[1] "Human PubMed Reference:".

[2] RAB11A - Cronfa NCBI

[2]

[1]