RAB1A

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB1A yw RAB1A a elwir hefyd yn RAB1A, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p14.

RAB1A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2FOL, 2WWX, 3L0I, 3SFV, 3TKL, 4FMB, 4FMC, 4FMD, 4FME, 4IRU, 4JVS
Dynodwyr
Cyfenwau	RAB1A, RAB1, YPT1, member RAS oncogene family
Dynodwyr allanol	OMIM: 179508 HomoloGene: 36154 GeneCards: RAB1A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GTP binding • GO:0001948, GO:0016582 protein binding • cadherin binding • GO:0006184 GTPase activity Cydrannau o'r gell • cytoplasm • cytosol • endosome • Golgi apparatus • endoplasmic reticulum membrane • bilen • melanosome • Golgi membrane • early endosome • Reticwlwm endoplasmig • extracellular exosome • transport vesicle membrane Prosesau biolegol • COPII-coated vesicle cargo loading • endocytosis • establishment of endothelial intestinal barrier • Golgi organization • vesicle transport along microtubule • autophagosome assembly • positive regulation of glycoprotein metabolic process • autophagy • endoplasmic reticulum to Golgi vesicle-mediated transport • COPII vesicle coating • melanosome transport • growth hormone secretion • defense response to bacterium • protein transport • substrate adhesion-dependent cell spreading • cell migration • vesicle-mediated transport • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum • cilium assembly • GO:0090623, GO:1903835, GO:0007092, GO:0051488, GO:0051487 positive regulation of ubiquitin protein ligase activity • post-translational protein modification • GO:0015915 transport • intracellular protein transport • Rab protein signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5861	n/a
Ensembl	ENSG00000138069	n/a
UniProt	P62820	n/a
RefSeq (mRNA)	NM_004161 NM_015543	n/a
RefSeq (protein)	NP_004152 NP_056358	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAB1A.

• RAB1
• YPT1

Llyfryddiaeth

• "Tissue-based quantitative proteome analysis of human hepatocellular carcinoma using tandem mass tags. ". Biomarkers. 2017. PMID 27467182.
• "Regulatory Implications of Non-Trivial Splicing: Isoform 3 of Rab1A Shows Enhanced Basal Activity and Is Not Controlled by Accessory Proteins. ". J Mol Biol. 2016. PMID 26953259.
• "Inhibition of RAB1A suppresses epithelial-mesenchymal transition and proliferation of triple-negative breast cancer cells. ". Oncol Rep. 2017. PMID 28184936.
• "Discovery of Rab1 binding sites using an ensemble of clustering methods. ". Proteins. 2017. PMID 28120477.
• "Expression of Rab1A is upregulated in human lung cancer and associated with tumor size and T stage.". Aging (Albany NY). 2016. PMID 27902464.