RAB1B

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB1B yw RAB1B a elwir hefyd yn RAB1B, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q13.2.

RAB1B
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3JZA, 3NKV, 4HLQ, 4I1O
Dynodwyr
Cyfenwau	RAB1B, member RAS oncogene family
Dynodwyr allanol	OMIM: 612565 HomoloGene: 128838 GeneCards: RAB1B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GTP binding • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity Cydrannau o'r gell • cytoplasm • phagophore assembly site membrane • Golgi apparatus • bilen • Golgi membrane • transport vesicle • mitocondria • extracellular exosome • endoplasmic reticulum-Golgi intermediate compartment membrane • endoplasmic reticulum-Golgi intermediate compartment • endoplasmic reticulum membrane • cytosol • perinuclear region of cytoplasm Prosesau biolegol • establishment of endothelial intestinal barrier • positive regulation of glycoprotein metabolic process • autophagy • regulation of autophagosome assembly • endoplasmic reticulum to Golgi vesicle-mediated transport • COPII vesicle coating • protein transport • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum • post-translational protein modification • GO:0015915 transport • intracellular protein transport • Rab protein signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	81876	n/a
Ensembl	ENSG00000174903	n/a
UniProt	Q9H0U4	n/a
RefSeq (mRNA)	NM_030981	n/a
RefSeq (protein)	NP_112243	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Llyfryddiaeth

• "Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB. ". EMBO Rep. 2013. PMID 23288104.
• "Role of Rab1b in COPII dynamics and function. ". Eur J Cell Biol. 2011. PMID 21093099.
• "Knockdown of Rap1b Enhances Apoptosis and Autophagy in Gastric Cancer Cells via the PI3K/Akt/mTOR Pathway. ". Oncol Res. 2016. PMID 27712585.
• "Loss of RAB1B promotes triple-negative breast cancer metastasis by activating TGF-β/SMAD signaling. ". Oncotarget. 2015. PMID 25970785.
• "Rab1b overexpression modifies Golgi size and gene expression in HeLa cells and modulates the thyrotrophin response in thyroid cells in culture.". Mol Biol Cell. 2013. PMID 23325787.