RAD9A

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAD9A yw RAD9A a elwir hefyd yn RAD9 checkpoint clamp component A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q13.2.

RAD9A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3A1J, 3G65, 3GGR
Dynodwyr
Cyfenwau	RAD9A, RAD9, RAD9 checkpoint clamp component A
Dynodwyr allanol	OMIM: 603761 HomoloGene: 32118 GeneCards: RAD9A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • SH3 domain binding • histone deacetylase binding • exodeoxyribonuclease III activity • GO:0001948, GO:0016582 protein binding • 3'-5' exonuclease activity • enzyme binding • nuclease activity • exonuclease activity • hydrolase activity • protein kinase binding Cydrannau o'r gell • cytoplasm • nucleoplasm • checkpoint clamp complex • cnewyllyn cell Prosesau biolegol • cell cycle checkpoint signaling • mitotic intra-S DNA damage checkpoint signaling • DNA damage checkpoint signaling • cellular response to DNA damage stimulus • DNA replication checkpoint signaling • positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage • cellular response to ionizing radiation • nucleic acid phosphodiester bond hydrolysis • GO:0100026 DNA repair • DNA replication • regulation of signal transduction by p53 class mediator Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5883	n/a
Ensembl	ENSG00000172613	n/a
UniProt	Q99638	n/a
RefSeq (mRNA)	NM_001243224 NM_004584	n/a
RefSeq (protein)	NP_001230153 NP_004575	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAD9A.

• RAD9

Llyfryddiaeth

• "Cell cycle-dependent processing of DNA lesions controls localization of Rad9 to sites of genotoxic stress. ". Cell Cycle. 2009. PMID 19411845.
• "Localization of hRad9 in breast cancer. ". BMC Cancer. 2008. PMID 18616832.
• "The checkpoint clamp protein Rad9 facilitates DNA-end resection and prevents alternative non-homologous end joining. ". Cell Cycle. 2014. PMID 25485590.
• "Checkpoint protein Rad9 plays an important role in nucleotide excision repair. ". DNA Repair (Amst). 2013. PMID 23433811.
• "Reduced mRNA and protein expression of the genomic caretaker RAD9A in primary fibroblasts of individuals with childhood and independent second cancer.". PLoS One. 2011. PMID 21991345.