RBM17

Protein sy'n cael ei godio yn y corff dynol gan y genyn RBM17 yw RBM17 a elwir hefyd yn Splicing factor 45 a RNA binding motif protein 17 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 10, band 10p15.1.

RBM17
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2PE8, 2PEH
Dynodwyr
Cyfenwau	RBM17, SPF45, RNA binding motif protein 17
Dynodwyr allanol	OMIM: 606935 HomoloGene: 13162 GeneCards: RBM17
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • RNA binding • nucleic acid binding Cydrannau o'r gell • spliceosomal complex • cnewyllyn cell • nucleoplasm • GO:0009327 protein-containing complex Prosesau biolegol • mRNA processing • alternative mRNA splicing, via spliceosome • RNA splicing • mRNA splicing, via spliceosome • GO:0100026 DNA repair • regulation of RNA splicing • regulation of alternative mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	84991	n/a
Ensembl	ENSG00000134453	n/a
UniProt	Q96I25	n/a
RefSeq (mRNA)	NM_032905 NM_001145547	n/a
RefSeq (protein)	NP_001139019 NP_116294	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RBM17.

• SPF45

Llyfryddiaeth

• "Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. ". Nat Genet. 2007. PMID 17676041.
• "Human splicing factor SPF45 (RBM17) confers broad multidrug resistance to anticancer drugs when overexpressed--a phenotype partially reversed by selective estrogen receptor modulators. ". Cancer Res. 2005. PMID 16061639.
• "Mitogen-activated protein kinase phosphorylation of splicing factor 45 (SPF45) regulates SPF45 alternative splicing site utilization, proliferation, and cell adhesion. ". Mol Cell Biol. 2012. PMID 22615491.
• "Human SPF45, a splicing factor, has limited expression in normal tissues, is overexpressed in many tumors, and can confer a multidrug-resistant phenotype to cells. ". Am J Pathol. 2003. PMID 14578179.
• "Structural basis of the phosphorylation dependent complex formation of neurodegenerative disease protein Ataxin-1 and RBM17.". Biochem Biophys Res Commun. 2014. PMID 24858692.