REG3A

Protein sy'n cael ei godio yn y corff dynol gan y genyn REG3A yw REG3A a elwir hefyd yn Regenerating family member 3 alpha (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p12.

REG3A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UV0, 2GO0, 4MTH
Dynodwyr
Cyfenwau	REG3A, HIP, HIP/PAP, INGAP, PAP, PAP-H, PAP1, PBCGF, REG-III, REG3, regenerating family member 3 alpha
Dynodwyr allanol	OMIM: 167805 HomoloGene: 130506 GeneCards: REG3A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • carbohydrate binding • identical protein binding • transmembrane signaling receptor activity • peptidoglycan binding • oligosaccharide binding Cydrannau o'r gell • cytoplasm • extracellular region • extracellular space Prosesau biolegol • inflammatory response • multicellular organism development • negative regulation of keratinocyte differentiation • positive regulation of keratinocyte proliferation • cell population proliferation • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules • positive regulation of wound healing • acute-phase response • antimicrobial humoral response • positive regulation of cell population proliferation • response to peptide hormone • cell wall disruption in other organism • antimicrobial humoral immune response mediated by antimicrobial peptide Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5068	n/a
Ensembl	ENSG00000172016	n/a
UniProt	Q06141	n/a
RefSeq (mRNA)	NM_138938 NM_002580 NM_138937	n/a
RefSeq (protein)	NP_002571 NP_620354 NP_620355	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn REG3A.

• HIP
• PAP
• PAP1
• REG3
• INGAP
• PAP-H
• PBCGF
• HIP/PAP
• REG-III

Llyfryddiaeth

• "Up-regulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk. ". Oncotarget. 2016. PMID 26646797.
• "Serum regenerating islet-derived 3-alpha is a biomarker of mucosal enteropathies. ". Aliment Pharmacol Ther. 2014. PMID 25112824.
• "High incidence of extensive chronic graft-versus-host disease in patients with the REG3A rs7588571 non-GG genotype. ". PLoS One. 2017. PMID 28945764.
• "PAP/REG3A favors perineural invasion in pancreatic adenocarcinoma and serves as a prognostic marker. ". Cell Mol Life Sci. 2017. PMID 28656348.
• "Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.". Gene. 2016. PMID 26719042.