RHO

Protein sy'n cael ei godio yn y corff dynol gan y genyn RHO yw RHO a elwir hefyd yn Rhodopsin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3q22.1.

RHO
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4ZWJ, 5DGY
Dynodwyr
Cyfenwau	RHO, CSNBAD1, OPN2, RP4, rhodopsin, Rhodopsin, visual purple
Dynodwyr allanol	OMIM: 180380 HomoloGene: 68068 GeneCards: RHO
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • signal transducer activity • metal ion binding • photoreceptor activity • GO:0001948, GO:0016582 protein binding • G protein-coupled receptor activity • 11-cis retinal binding • G protein-coupled photoreceptor activity Cydrannau o'r gell • Golgi-associated vesicle membrane • Golgi apparatus • Golgi membrane • photoreceptor outer segment • cell-cell junction • integral component of plasma membrane • bilen • photoreceptor inner segment • ciliary membrane • Cellbilen • photoreceptor inner segment membrane • photoreceptor outer segment membrane • integral component of membrane • photoreceptor disc membrane • cell projection Prosesau biolegol • retina development in camera-type eye • sensory perception of light stimulus • GO:0072468 signal transduction • response to stimulus • detection of light stimulus • absorption of visible light • cellular response to light stimulus • protein phosphorylation • response to light stimulus • regulation of rhodopsin mediated signaling pathway • retinoid metabolic process • phototransduction • phototransduction, visible light • photoreceptor cell maintenance • golwg • G protein-coupled receptor signaling pathway • rhodopsin mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6010	n/a
Ensembl	ENSG00000163914	n/a
UniProt	P08100	n/a
RefSeq (mRNA)	NM_000539	n/a
RefSeq (protein)	NP_000530	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RHO.

• RP4
• OPN2
• CSNBAD1

Llyfryddiaeth

• "Effects of Pathogenic Variations in the Human Rhodopsin Gene (hRHO) on the Predicted Accessibility for a Lead Candidate Ribozyme. ". Invest Ophthalmol Vis Sci. 2017. PMID 28715844.
• "Wild-type opsin does not aggregate with a misfolded opsin mutant. ". Biochim Biophys Acta. 2016. PMID 27117643.
• "Genetic Analysis of the Rhodopsin Gene Identifies a Mosaic Dominant Retinitis Pigmentosa Mutation in a Healthy Individual. ". Invest Ophthalmol Vis Sci. 2016. PMID 26962691.
• "Functional role of positively selected amino acid substitutions in mammalian rhodopsin evolution. ". Sci Rep. 2016. PMID 26865329.
• "Identification of a rhodopsin gene mutation in a large family with autosomal dominant retinitis pigmentosa.". Sci Rep. 2016. PMID 26794436.