RING1

Protein sy'n cael ei godio yn y corff dynol gan y genyn RING1 yw RING1 a elwir hefyd yn Ring finger protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6p21.32.

RING1
Dynodwyr
Cyfenwau	RING1, RING1A, RNF1, ring finger protein 1
Dynodwyr allanol	OMIM: 602045 HomoloGene: 68283 GeneCards: RING1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • chromatin binding • metal ion binding • GO:0001948, GO:0016582 protein binding • ubiquitin-protein transferase activator activity • transferase activity Cydrannau o'r gell • nuclear speck • nuclear body • sex chromatin • ubiquitin ligase complex • nucleoplasm • PcG protein complex • cnewyllyn cell • cytosol • PRC1 complex Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • histone H2A monoubiquitination • transcription, DNA-templated • protein ubiquitination • GO:0048552 regulation of catalytic activity • GO:0045996 negative regulation of transcription, DNA-templated • histone ubiquitination • camera-type eye morphogenesis • anterior/posterior pattern specification • negative regulation of G0 to G1 transition • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6015	n/a
Ensembl	ENSG00000204227	n/a
UniProt	Q06587	n/a
RefSeq (mRNA)	NM_002931	n/a
RefSeq (protein)	NP_002922	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RING1.

• RNF1
• RING1A

Llyfryddiaeth

• "New genes in the class II region of the human major histocompatibility complex. ". Genomics. 1991. PMID 1906426.
• "Nuclear envelope-distributed CD147 interacts with and inhibits the transcriptional function of RING1 and promotes melanoma cell motility. ". PLoS One. 2017. PMID 28832687.
• "Upregulated expression of polycomb protein Ring1 contributes to poor prognosis and accelerated proliferation in human hepatocellular carcinoma. ". Tumour Biol. 2015. PMID 26141041.
• "Polycomb group oncogene RING1 is over-expressed in non-small cell lung cancer. ". Pathol Oncol Res. 2014. PMID 24414991.
• "Identification and preliminary characterization of a protein motif related to the zinc finger.". Proc Natl Acad Sci U S A. 1993. PMID 7681583.