RNF38

Protein sy'n cael ei godio yn y corff dynol gan y genyn RNF38 yw RNF38 a elwir hefyd yn Ring finger protein 38 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9p13.2.

RNF38
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X4J, 4V3K, 4V3L
Dynodwyr
Cyfenwau	RNF38, ring finger protein 38
Dynodwyr allanol	OMIM: 612488 HomoloGene: 32550 GeneCards: RNF38
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • GO:0050372 ubiquitin-protein transferase activity • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • transferase activity Cydrannau o'r gell • sperm flagellum • cnewyllyn cell • nucleoplasm Prosesau biolegol • male gonad development • protein ubiquitination • proteasome-mediated ubiquitin-dependent protein catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	152006	n/a
Ensembl	ENSG00000137075	n/a
UniProt	Q9H0F5	n/a
RefSeq (mRNA)	NM_022781 NM_194328 NM_194329 NM_194330 NM_194331 NM_194332	n/a
RefSeq (protein)	NP_073618 NP_919309 NP_919310 NP_919311 NP_919313	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Llyfryddiaeth

• "Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions. ". Development. 2003. PMID 12874135.
• "Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver. ". Proc Natl Acad Sci U S A. 2001. PMID 11752456.
• "Cloning and characterization of a novel human gene RNF38 encoding a conserved putative protein with a RING finger domain. ". Biochem Biophys Res Commun. 2002. PMID 12074600.
• "RNF38 encodes a nuclear ubiquitin protein ligase that modifies p53. ". Biochem Biophys Res Commun. 2013. PMID 23973461.
• "Activation of a primed RING E3-E2-ubiquitin complex by non-covalent ubiquitin.". Mol Cell. 2015. PMID 25801170.