RPA3

Protein sy'n cael ei godio yn y corff dynol gan y genyn RPA3 yw RPA3 a elwir hefyd yn Replication protein A3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p21.3.

RPA3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1L1O, 1QUQ, 2PI2, 2PQA, 2Z6K, 3KDF
Dynodwyr
Cyfenwau	RPA3, REPA3, RP-A p14, replication protein A3
Dynodwyr allanol	OMIM: 179837 HomoloGene: 68285 GeneCards: RPA3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • single-stranded DNA binding • DNA binding • damaged DNA binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • DNA replication factor A complex • site of double-strand break Prosesau biolegol • DNA recombination • translesion synthesis • DNA replication • nucleotide-excision repair, DNA gap filling • transcription-coupled nucleotide-excision repair • regulation of cell population proliferation • nucleotide-excision repair, DNA incision • error-free translesion synthesis • cellular response to DNA damage stimulus • regulation of mitotic cell cycle • regulation of cellular response to heat • interstrand cross-link repair • error-prone translesion synthesis • nucleotide-excision repair, DNA incision, 5'-to lesion • nucleotide-excision repair, preincision complex stabilization • nucleotide-excision repair • GO:0100026 DNA repair • base-excision repair • double-strand break repair via homologous recombination • nucleotide-excision repair, preincision complex assembly • telomere maintenance • telomere maintenance via semi-conservative replication • G1/S transition of mitotic cell cycle • DNA mismatch repair • nucleotide-excision repair, DNA incision, 3'-to lesion • regulation of signal transduction by p53 class mediator Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6119	n/a
Ensembl	ENSG00000106399	n/a
UniProt	P35244	n/a
RefSeq (mRNA)	NM_002947	n/a
RefSeq (protein)	NP_002938	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RPA3.

• REPA3
• RP-A*p14

Llyfryddiaeth

• "Replication protein A (RPA): the eukaryotic SSB. ". Crit Rev Biochem Mol Biol. 1999. PMID 10473346.
• "The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding. ". EMBO J. 1999. PMID 10449415.
• "Elevated Expression of RPA3 Is Involved in Gastric Cancer Tumorigenesis and Associated with Poor Patient Survival. ". Dig Dis Sci. 2017. PMID 28766245.
• "TP53 and RPA3 gene variations were associated with risk of glioma in a Chinese Han population. ". Cancer Biother Radiopharm. 2013. PMID 23573956.
• "Dynamic light-scattering analysis of full-length human RPA14/32 dimer: purification, crystallization and self-association.". Acta Crystallogr D Biol Crystallogr. 2001. PMID 11173472.