SCO1

Protein sy'n cael ei godio yn y corff dynol gan y genyn SCO1 yw SCO1 a elwir hefyd yn SCO1, cytochrome c oxidase assembly protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17p13.1.

SCO1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WP0, 2GGT, 2GQK, 2GQL, 2GQM, 2GT5, 2GT6, 2GVP, 2HRF, 2HRN
Dynodwyr
Cyfenwau	SCO1, SCOD1, SCO1 cytochrome c oxidase assembly protein, cytochrome c oxidase assembly protein, SCO cytochrome c oxidase assembly protein 1, synthesis of cytochrome C oxidase 1, MC4DN4
Dynodwyr allanol	OMIM: 603644 HomoloGene: 3374 GeneCards: SCO1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • copper ion binding • metal ion binding Cydrannau o'r gell • Myoffibril • host cell mitochondrial intermembrane space • mitocondria • mitochondrial inner membrane • integral component of mitochondrial inner membrane • bilen • integral component of membrane Prosesau biolegol • cellular copper ion homeostasis • generation of precursor metabolites and energy • copper ion transport • respiratory chain complex IV assembly • negative regulation of proteasomal protein catabolic process • mitochondrial cytochrome c oxidase assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6341	n/a
Ensembl	ENSG00000133028	n/a
UniProt	O75880	n/a
RefSeq (mRNA)	NM_004589	n/a
RefSeq (protein)	NP_004580	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SCO1.

• SCOD1

Llyfryddiaeth

• "Loop recognition and copper-mediated disulfide reduction underpin metal site assembly of CuA in human cytochrome oxidase. ". Proc Natl Acad Sci U S A. 2015. PMID 26351686.
• "Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer. ". Proc Natl Acad Sci U S A. 2008. PMID 18458339.
• "A hint for the function of human Sco1 from different structures. ". Proc Natl Acad Sci U S A. 2006. PMID 16735468.
• "Mutations of the SCO1 gene in mitochondrial cytochrome c oxidase deficiency with neonatal-onset hepatic failure and encephalopathy. ". Am J Hum Genet. 2000. PMID 11013136.
• "Accumulation of the cytochrome c oxidase subunits I and II in yeast requires a mitochondrial membrane-associated protein, encoded by the nuclear SCO1 gene.". Mol Gen Genet. 1989. PMID 2543907.