SEC23A

Protein sy'n cael ei godio yn y corff dynol gan y genyn SEC23A yw SEC23A a elwir hefyd yn Protein transport protein Sec23A a Sec23 homolog A, coat complex II component (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q21.1.

SEC23A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2NUP, 2NUT, 2YRC, 2YRD, 3EFO, 3EG9, 3EGD, 3EGX
Dynodwyr
Cyfenwau	SEC23A, CLSD, Sec23 homolog A, coat complex II component, hSec23A, Sec23 homolog A, COPII coat complex component
Dynodwyr allanol	OMIM: 610511 HomoloGene: 4642 GeneCards: SEC23A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • zinc ion binding • metal ion binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity Cydrannau o'r gell • bilen • Golgi membrane • perinuclear region of cytoplasm • COPII-coated ER to Golgi transport vesicle • Reticwlwm endoplasmig • extrinsic component of membrane • COPII vesicle coat • endoplasmic reticulum exit site • cytoplasm • endoplasmic reticulum membrane • cytosol • ER to Golgi transport vesicle membrane • GO:0016023 cytoplasmic vesicle Prosesau biolegol • antigen processing and presentation of exogenous peptide antigen via MHC class II • antigen processing and presentation of peptide antigen via MHC class I • endoplasmic reticulum to Golgi vesicle-mediated transport • COPII vesicle coating • protein transport • intracellular protein transport • vesicle-mediated transport • COPII-coated vesicle cargo loading • COPII-coated vesicle budding • regulation of COPII vesicle coating • Golgi organization • regulation of cell shape • macroautophagy • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10484	n/a
Ensembl	ENSG00000100934	n/a
UniProt	Q15436	n/a
RefSeq (mRNA)	NM_006364	n/a
RefSeq (protein)	NP_006355	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SEC23A.

• CLSD
• hSec23A

Llyfryddiaeth

• "A novel dysmorphic syndrome with open calvarial sutures and sutural cataracts maps to chromosome 14q13-q21. ". Hum Genet. 2003. PMID 12677423.
• "MicroRNA-21 promotes proliferation, migration, and invasion of colorectal cancer, and tumor growth associated with down-regulation of sec23a expression. ". BMC Cancer. 2016. PMID 27495250.
• "Endoplasmic reticulum stress reduces COPII vesicle formation and modifies Sec23a cycling at ERESs. ". FEBS Lett. 2013. PMID 23994533.
• "Hypomorphic mutations of SEC23B gene account for mild phenotypes of congenital dyserythropoietic anemia type II. ". Blood Cells Mol Dis. 2013. PMID 23453696.
• "Cranio-lenticulo-sutural dysplasia associated with defects in collagen secretion.". Clin Genet. 2011. PMID 21039434.