SGK3

Protein sy'n cael ei godio yn y corff dynol gan y genyn SGK3 yw SGK3 a elwir hefyd yn Serine/threonine-protein kinase Sgk3 a C8orf44-SGK3 readthrough (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8q13.1.

SGK3
Dynodwyr
Cyfenwau	SGK3, CISK, SGK2, SGKL, serum/glucocorticoid regulated kinase family member 3
Dynodwyr allanol	OMIM: 607591 HomoloGene: 56582 GeneCards: SGK3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • protein kinase activity • nucleotide binding • sodium channel regulator activity • calcium channel regulator activity • kinase activity • potassium channel regulator activity • GO:0001948, GO:0016582 protein binding • phosphatidylinositol binding • chloride channel regulator activity • ATP binding • protein serine/threonine kinase activity Cydrannau o'r gell • recycling endosome • cytosol • endosome • early endosome • GO:0016023 cytoplasmic vesicle Prosesau biolegol • regulation of apoptotic process • GO:0007243 intracellular signal transduction • regulation of cell migration • positive regulation of transporter activity • phosphorylation • protein phosphorylation • cludo transmembrane rhwng ïonau • regulation of cell population proliferation • GO:0035404 peptidyl-serine phosphorylation • regulation of DNA-binding transcription factor activity • regulation of cell growth • negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23678	n/a
Ensembl	ENSG00000104205	n/a
UniProt	Q96BR1	n/a
RefSeq (mRNA)	NM_170709 NM_001033578 NM_013257	n/a
RefSeq (protein)	NP_001191102 NP_001028750 NP_037389 NP_733827	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SGK3.

• CISK
• SGK2
• SGKL

Llyfryddiaeth

• "Upregulation of HERG channels by the serum and glucocorticoid inducible kinase isoform SGK3. ". Cell Physiol Biochem. 2006. PMID 17167223.
• "INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas. ". Oncotarget. 2015. PMID 26573229.
• "Loss of serum and glucocorticoid-regulated kinase 3 (SGK3) does not affect proliferation and survival of multiple myeloma cell lines. ". PLoS One. 2015. PMID 25837824.
• "SGK3 is associated with estrogen receptor expression in breast cancer. ". Breast Cancer Res Treat. 2012. PMID 22576469.
• "Serum and glucocorticoid kinase 3 at 8q13.1 promotes cell proliferation and survival in hepatocellular carcinoma.". Hepatology. 2012. PMID 22262416.