SH2B1

Protein sy'n cael ei godio yn y corff dynol gan y genyn SH2B1 yw SH2B1 a elwir hefyd yn SH2B adapter protein 1 a SH2B adaptor protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p11.2.

SH2B1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2HDV, 2HDX
Dynodwyr
Cyfenwau	SH2B1, PSM, SH2B, SH2B adaptor protein 1
Dynodwyr allanol	OMIM: 608937 HomoloGene: 32122 GeneCards: SH2B1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • signaling adaptor activity • GO:0001948, GO:0016582 protein binding • transmembrane receptor protein tyrosine kinase adaptor activity Cydrannau o'r gell • cytosol • cnewyllyn cell • bilen • cytoplasm • Cellbilen Prosesau biolegol • positive regulation of signal transduction • positive regulation of mitotic nuclear division • blood coagulation • lamellipodium assembly • GO:0072468 signal transduction • regulation of DNA biosynthetic process • transmembrane receptor protein tyrosine kinase signaling pathway • GO:0007243 intracellular signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	25970	n/a
Ensembl	ENSG00000178188	n/a
UniProt	Q9NRF2	n/a
RefSeq (mRNA)	NM_001145795 NM_001145796 NM_001145797 NM_001145812 NM_001308293 NM_001308294 NM_015503 NM_001387404 NM_001387430	n/a
RefSeq (protein)	NP_001139267 NP_001139268 NP_001139269 NP_001139284 NP_001295222 NP_001295223 NP_056318	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SH2B1.

• PSM
• SH2B

Llyfryddiaeth

• "Genetic and structural variation in the SH2B1 gene in the Belgian population. ". Mol Genet Metab. 2015. PMID 26031769.
• "SH2B1 CpG-SNP is associated with body weight reduction in obese subjects following a dietary restriction program. ". Ann Nutr Metab. 2015. PMID 25471250.
• "Discordant phenotypes in monozygotic twins with 16p11.2 microdeletions including the SH2B1 gene. ". Am J Med Genet A. 2017. PMID 28544142.
• "SH2B1 modulates chromatin state and MyoD occupancy to enhance expressions of myogenic genes. ". Biochim Biophys Acta. 2017. PMID 28039048.
• "Evidence for Association between SH2B1 Gene Variants and Glycated Hemoglobin in Nondiabetic European American Young Adults: The Add Health Study.". Ann Hum Genet. 2016. PMID 27530450.