SH3GLB1

Protein sy'n cael ei godio yn y corff dynol gan y genyn SH3GLB1 yw SH3GLB1 a elwir hefyd yn SH3 domain containing GRB2 like, endophilin B1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p22.3.

SH3GLB1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X43
Dynodwyr
Cyfenwau	SH3GLB1, Bif-1, PPP1R70, dJ612B15.2, CGI-61, SH3 domain containing GRB2 like endophilin B1, SH3 domain containing GRB2 like, endophilin B1
Dynodwyr allanol	OMIM: 609287 HomoloGene: 9337 GeneCards: SH3GLB1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • GO:0001948, GO:0016582 protein binding • identical protein binding • lipid binding • cadherin binding Cydrannau o'r gell • cytoplasm • Golgi apparatus • bilen • Golgi membrane • mitochondrial outer membrane • autophagosome membrane • midbody • mitocondria • extracellular exosome • GO:0016023 cytoplasmic vesicle • cytosol Prosesau biolegol • cellular response to glucose starvation • regulation of cytokinesis • regulation of protein stability • positive regulation of autophagosome assembly • positive regulation of autophagy • positive regulation of protein targeting to mitochondrion • cellular response to amino acid starvation • receptor catabolic process • autophagy • protein complex oligomerization • membrane fission • positive regulation of protein oligomerization • positive regulation of membrane tubulation • autophagic cell death • regulation of macroautophagy • protein localization to vacuolar membrane • GO:0097285 apoptotic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51100	n/a
Ensembl	ENSG00000097033	n/a
UniProt	Q9Y371	n/a
RefSeq (mRNA)	NM_001206651 NM_001206652 NM_001206653 NM_016009	n/a
RefSeq (protein)	NP_001193580 NP_001193581 NP_001193582 NP_057093	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SH3GLB1.

• Bif-1
• CGI-61
• PPP1R70
• dJ612B15.2

Llyfryddiaeth

• "Down-regulation of Bax-interacting factor 1 in human pancreatic ductal adenocarcinoma. ". Pancreas. 2011. PMID 21283040.
• "Somatic mutation of pro-cell death Bif-1 gene is rare in common human cancers. ". APMIS. 2008. PMID 19132989.
• "Bax-interacting factor-1 inhibits cell proliferation and promotes apoptosis in prostate cancer cells. ". Oncol Rep. 2016. PMID 27748942.
• "Association of Endophilin B1 with Cytoplasmic Vesicles. ". Biophys J. 2016. PMID 27508440.
• "Bif-1 suppresses breast cancer cell migration by promoting EGFR endocytic degradation.". Cancer Biol Ther. 2012. PMID 22785202.