SNAP25

Protein sy'n cael ei godio yn y corff dynol gan y genyn SNAP25 yw SNAP25 a elwir hefyd yn Synaptosome associated protein 25 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20p12.2.

SNAP25
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1KIL, 1XTG, 3DDA, 3RK2, 3RK3, 3RL0, 3ZUR, 2N1T, 3DDB
Dynodwyr
Cyfenwau	SNAP25, CMS18, RIC-4, RIC4, SEC9, SNAP, SNAP-25, bA416N4.2, dJ1068F16.2, SUP, synaptosome associated protein 25kDa, synaptosome associated protein 25
Dynodwyr allanol	OMIM: 600322 HomoloGene: 13311 GeneCards: SNAP25
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • SNAP receptor activity • calcium-dependent protein binding • GO:0001948, GO:0016582 protein binding • SNARE binding • syntaxin-1 binding • voltage-gated potassium channel activity • syntaxin binding Cydrannau o'r gell • cytoplasm • fesigl • cytosol • bilen • growth cone • myelin sheath • BLOC-1 complex • voltage-gated potassium channel complex • Cellbilen • synapse • synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex • cell junction • trans-Golgi network • SNARE complex • perinuclear region of cytoplasm • neuron projection • synaptic vesicle • presynaptic membrane • axon • specific granule membrane • somatodendritic compartment • tertiary granule membrane • postsynapse • extrinsic component of cytoplasmic side of plasma membrane • Cytosgerbwd • glutamatergic synapse Prosesau biolegol • associative learning • regulation of neuron projection development • synaptic vesicle docking • locomotory behavior • regulation of insulin secretion • synaptic vesicle exocytosis • synaptic vesicle fusion to presynaptic active zone membrane • glutamate secretion • neurotransmitter uptake • synaptic vesicle priming • regulation of establishment of protein localization • GO:0010554 neurotransmitter secretion • long-term potentiation • chemical synaptic transmission • positive regulation of synaptic plasticity • neutrophil degranulation • short-term synaptic potentiation • exocytic insertion of neurotransmitter receptor to postsynaptic membrane • neurotransmitter receptor internalization • exocytosis • vesicle fusion • potassium ion transmembrane transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6616	n/a
Ensembl	ENSG00000132639	n/a
UniProt	P60880	n/a
RefSeq (mRNA)	NM_003081 NM_130811 NM_001322902 NM_001322903 NM_001322904 NM_001322905 NM_001322906 NM_001322907 NM_001322908 NM_001322909 NM_001322910	n/a
RefSeq (protein)	NP_001309831 NP_001309832 NP_001309833 NP_001309834 NP_001309835 NP_001309836 NP_001309837 NP_001309838 NP_001309839 NP_003072 NP_570824	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SNAP25.

• SUP
• RIC4
• SEC9
• SNAP
• CMS18
• RIC-4
• SNAP-25
• bA416N4.2
• dJ1068F16.2

Llyfryddiaeth

• "A Multilevel Functional Study of a SNAP25At-Risk Variant for Bipolar Disorder and Schizophrenia. ". J Neurosci. 2017. PMID 28972123.
• "Detection of lower levels of SNAP25 using multiple microarray systems and its functional significance in medulloblastoma. ". Int J Mol Med. 2017. PMID 28339008.
• "Synaptosome-Associated Protein 25 (SNAP25) Gene Association Analysis Revealed Risk Variants for ASD, in Iranian Population. ". J Mol Neurosci. 2017. PMID 27888397.
• "SNAP-25 gene variations and attention-deficit hyperactivity disorder in Iranian population. ". Neurol Res. 2016. PMID 27627841.
• "Two SNAP-25 genetic variants in the binding site of multiple microRNAs and susceptibility of ADHD: A meta-analysis.". J Psychiatr Res. 2016. PMID 27380186.