SPTB

Protein sy'n cael ei godio yn y corff dynol gan y genyn SPTB yw SPTB a elwir hefyd yn Spectrin beta chain, erythrocytic a Spectrin beta, erythrocytic (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q23.3.

SPTB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1S35, 3EDU, 3F57, 3KBT, 3KBU, 3LBX
Dynodwyr
Cyfenwau	SPTB, EL3, HS2, HSPTB1, SPH2, spectrin beta, erythrocytic
Dynodwyr allanol	OMIM: 182870 HomoloGene: 295 GeneCards: SPTB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • actin filament binding • structural constituent of cytoskeleton • GO:0001948, GO:0016582 protein binding • ankyrin binding • actin binding Cydrannau o'r gell • spectrin • intrinsic component of the cytoplasmic side of the plasma membrane • cell surface • cell cortex • actin cytoskeleton • spectrin-associated cytoskeleton • Cytosgerbwd • cytoplasm • Golgi apparatus • cytosol • GO:0009327 protein-containing complex Prosesau biolegol • MAPK cascade • axon guidance • endoplasmic reticulum to Golgi vesicle-mediated transport • actin filament capping • cytoskeleton organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6710	n/a
Ensembl	ENSG00000070182	n/a
UniProt	P11277	n/a
RefSeq (mRNA)	NM_000347 NM_001024858 NM_001355436 NM_001355437	n/a
RefSeq (protein)	NP_001020029 NP_001342365 NP_001342366	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SPTB.

• EL3
• HS2
• SPH2
• HSPTB1

Llyfryddiaeth

• "ATP-dependent mechanism protects spectrin against glycation in human erythrocytes. ". J Biol Chem. 2010. PMID 20724481.
• "The structure of the ankyrin-binding site of beta-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties. ". Blood. 2009. PMID 19168783.
• "Targeted next generation sequencing identifies a novel β-spectrin gene mutation A2059P in two Omani children with hereditary pyropoikilocytosis. ". Am J Hematol. 2017. PMID 28699249.
• "A new frameshift mutation of the β-spectrin gene associated with hereditary spherocytosis. ". Ann Hematol. 2017. PMID 27709257.
• "Key amino acid residues of ankyrin-sensitive phosphatidylethanolamine/phosphatidylcholine-lipid binding site of βI-spectrin.". PLoS One. 2011. PMID 21738695.