SSH2

Protein sy'n cael ei godio yn y corff dynol gan y genyn SSH2 yw SSH2 a elwir hefyd yn Slingshot protein phosphatase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q11.2.

SSH2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2NT2
Dynodwyr
Cyfenwau	SSH2, SSH-2, SSH-2L, slingshot protein phosphatase 2
Dynodwyr allanol	OMIM: 606779 HomoloGene: 14116 GeneCards: SSH2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein tyrosine phosphatase activity • GO:0098519, GO:0098518 phosphatase activity • actin binding • phosphoprotein phosphatase activity • hydrolase activity • protein tyrosine/serine/threonine phosphatase activity Cydrannau o'r gell • cytoplasm • Cytosgerbwd • extracellular space Prosesau biolegol • regulation of lamellipodium assembly • regulation of axonogenesis • regulation of actin polymerization or depolymerization • GO:0016576 protein dephosphorylation • peptidyl-tyrosine dephosphorylation • actin cytoskeleton organization • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • GO:0000767 cell morphogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	85464	n/a
Ensembl	ENSG00000141298	n/a
UniProt	Q76I76	n/a
RefSeq (mRNA)	NM_001282129 NM_001282130 NM_001282131 NM_033389	n/a
RefSeq (protein)	NP_001269058 NP_001269059 NP_001269060 NP_203747	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SSH2.

• SSH-2
• SSH-2L

Llyfryddiaeth

• "Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN). ". Oncogene. 2014. PMID 23416984.
• "Slingshot isoform-specific regulation of cofilin-mediated vascular smooth muscle cell migration and neointima formation. ". Arterioscler Thromb Vasc Biol. 2011. PMID 21868701.
• "Crystal structure of human slingshot phosphatase 2. ". Proteins. 2007. PMID 17427953.
• "Identification of genes expressed during myocardial development. ". Chin Med J (Engl). 2003. PMID 14527359.
• "GPCR-mediated PLCβγ/PKCβ/PKD signaling pathway regulates the cofilin phosphatase slingshot 2 in neutrophil chemotaxis.". Mol Biol Cell. 2015. PMID 25568344.