STK16

Protein sy'n cael ei godio yn y corff dynol gan y genyn STK16 yw STK16 a elwir hefyd yn Serine/threonine kinase 16 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q35.

STK16
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2BUJ
Dynodwyr
Cyfenwau	STK16, KRCT, MPSK, PKL12, TSF1, serine/threonine kinase 16, PSK, hPSK
Dynodwyr allanol	OMIM: 604719 HomoloGene: 2739 GeneCards: STK16
EC number	2.7.10.2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • protein kinase activity • nucleotide binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • non-membrane spanning protein tyrosine kinase activity • GO:0001948, GO:0016582 protein binding • ATP binding • kinase activity • protein serine/threonine kinase activity Cydrannau o'r gell • Golgi-associated vesicle • perinuclear region of cytoplasm • bilen • cytoplasm • cytosol Prosesau biolegol • protein autophosphorylation • peptidyl-tyrosine phosphorylation • protein phosphorylation • transcription by RNA polymerase II • phosphorylation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • cellular response to transforming growth factor beta stimulus Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8576	n/a
Ensembl	ENSG00000115661	n/a
UniProt	O75716	n/a
RefSeq (mRNA)	NM_001008910 NM_003691 NM_032768 NM_001330213 NM_001330214 NM_001330215	n/a
RefSeq (protein)	NP_001008910 NP_001317142 NP_001317143 NP_001317144	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn STK16.

• PSK
• KRCT
• MPSK
• TSF1
• hPSK
• PKL12

Llyfryddiaeth

• "Functional interaction between the Ser/Thr kinase PKL12 and N-acetylglucosamine kinase, a prominent enzyme implicated in the salvage pathway for GlcNAc recycling. ". J Biol Chem. 2002. PMID 11741987.
• "Structure of the human protein kinase MPSK1 reveals an atypical activation loop architecture. ". Structure. 2008. PMID 18184589.
• "Serine/threonine kinase 16 and MAL2 regulate constitutive secretion of soluble cargo in hepatic cells. ". Biochem J. 2014. PMID 25084525.
• "Identification and characterization of a myristylated and palmitylated serine/threonine protein kinase. ". Biochem Biophys Res Commun. 1999. PMID 10364453.
• "Nucleocytoplasmic shuttling of STK16 (PKL12), a Golgi-resident serine/threonine kinase involved in VEGF expression regulation.". Exp Cell Res. 2006. PMID 16310770.