SUCLG1

Protein sy'n cael ei godio yn y corff dynol gan y genyn SUCLG1 yw SUCLG1 a elwir hefyd yn Succinate-CoA ligase alpha subunit (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p11.2.

SUCLG1
Dynodwyr
Cyfenwau	SUCLG1, GALPHA, MTDPS9, SUCLA1, succinate-CoA ligase alpha subunit, succinate-CoA ligase GDP/ADP-forming subunit alpha
Dynodwyr allanol	OMIM: 611224 HomoloGene: 55785 GeneCards: SUCLG1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • ligase activity • catalytic activity • RNA binding • succinate-CoA ligase (ADP-forming) activity • succinate-CoA ligase (GDP-forming) activity • nucleoside diphosphate kinase activity • GDP binding • succinate-CoA ligase activity Cydrannau o'r gell • Cellbilen • mitocondria • mitochondrial inner membrane • extracellular exosome • cytosol • mitochondrial matrix • succinate-CoA ligase complex (GDP-forming) Prosesau biolegol • metabolaeth • cylch Krebs • succinyl-CoA metabolic process • succinate metabolic process • nucleoside diphosphate phosphorylation • nucleoside triphosphate biosynthetic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8802	n/a
Ensembl	ENSG00000163541	n/a
UniProt	P53597	n/a
RefSeq (mRNA)	NM_003849	n/a
RefSeq (protein)	NP_003840	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SUCLG1.

• GALPHA
• MTDPS9
• SUCLA1

Llyfryddiaeth

• "Marked mitochondrial DNA depletion associated with a novel SUCLG1 gene mutation resulting in lethal neonatal acidosis, multi-organ failure, and interrupted aortic arch. ". Mitochondrion. 2010. PMID 20227526.
• "New SUCLG1 patients expanding the phenotypic spectrum of this rare cause of mild methylmalonic aciduria. ". Mitochondrion. 2010. PMID 20197121.
• SUCLG1-Related Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form with Methylmalonic Aciduria. 1993. PMID 28358460.
• "Five novel SUCLG1 mutations in three Chinese patients with succinate-CoA ligase deficiency noticed by mild methylmalonic aciduria. ". Brain Dev. 2016. PMID 26028457.
• "The severity of phenotype linked to SUCLG1 mutations could be correlated with residual amount of SUCLG1 protein.". J Med Genet. 2010. PMID 20693550.