SYT4

Protein sy'n cael ei godio yn y corff dynol gan y genyn SYT4 yw SYT4 a elwir hefyd yn Synaptotagmin-4 a Synaptotagmin 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 18, band 18q12.3.

SYT4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UGK
Dynodwyr
Cyfenwau	SYT4, HsT1192, synaptotagmin 4
Dynodwyr allanol	OMIM: 600103 HomoloGene: 7559 GeneCards: SYT4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium ion binding • clathrin binding • phosphatidylserine binding • metal ion binding • GO:0001948, GO:0016582 protein binding • SNARE binding • syntaxin-1 binding • syntaxin binding • syntaxin-3 binding • protein homodimerization activity • protein heterodimerization activity • calcium-dependent phospholipid binding Cydrannau o'r gell • integral component of membrane • intracellular membrane-bounded organelle • bilen • synapse • synaptic vesicle membrane • cell junction • perinuclear region of cytoplasm • neuron projection • dense core granule • GO:0016023 cytoplasmic vesicle • dendrite • Golgi apparatus • fesigl • axon • Cellbilen • synaptic vesicle • integral component of Golgi membrane • integral component of synaptic vesicle membrane • secretory granule membrane • dense core granule membrane • somatodendritic compartment • neuronal cell body • neuron projection terminus • exocytic vesicle • astrocyte projection • microvesicle • glutamatergic synapse • integral component of neuronal dense core vesicle membrane Prosesau biolegol • cell differentiation • brain development • positive regulation of dendrite extension • negative regulation of vesicle fusion • GO:0010554 neurotransmitter secretion • exocytosis • vesicle fusion • calcium ion-regulated exocytosis of neurotransmitter • Cof • positive regulation of glutamate secretion • regulation of dopamine secretion • regulation of endocytosis • regulation of vesicle fusion • negative regulation of catecholamine secretion • positive regulation of calcium ion-dependent exocytosis • negative regulation of neurotransmitter secretion • negative regulation of short-term neuronal synaptic plasticity • vesicle fusion with vesicle • secretory granule maturation • negative regulation of protein secretion • negative regulation of retrograde trans-synaptic signaling by neuropeptide • regulation of calcium ion-dependent exocytosis • negative regulation of calcium ion-dependent exocytosis • trans-synaptic signaling by BDNF, modulating synaptic transmission • vesicle-mediated transport • calcium-ion regulated exocytosis • cellular response to calcium ion • regulation of presynaptic dense core granule exocytosis • negative regulation of dense core granule exocytosis • positive regulation of dense core granule exocytosis • negative regulation of synaptic vesicle exocytosis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6860	n/a
Ensembl	ENSG00000132872	n/a
UniProt	Q9H2B2	n/a
RefSeq (mRNA)	NM_020783	n/a
RefSeq (protein)	NP_065834	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SYT4.

• HsT1192

Llyfryddiaeth

• "Neuropeptide exocytosis involving synaptotagmin-4 and oxytocin in hypothalamic programming of body weight and energy balance. ". Neuron. 2011. PMID 21315262.
• "Upregulation of synaptotagmin IV inhibits transmitter release in PC12 cells with targeted synaptotagmin I knockdown. ". BMC Neurosci. 2010. PMID 20735850.
• "Synaptotagmin IV acts as a multi-functional regulator of Ca2+-dependent exocytosis. ". Neurochem Res. 2011. PMID 21153436.
• "Upregulation and axonal transport of synaptotagmin-IV in the direct-pathway medium spiny neurons in hemi-parkinsonian rats induced by dopamine D1 receptor stimulation. ". Eur J Neurosci. 2016. PMID 26750488.
• "The human synaptotagmin IV gene defines an evolutionary break point between syntenic mouse and human chromosome regions but retains ligand inducibility and tissue specificity.". J Biol Chem. 2000. PMID 10938284.