TBP

Protein sy'n cael ei godio yn y corff dynol gan y genyn TBP yw TBP a elwir hefyd yn TATA-box binding protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6q27.

TBP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1TGH, 1C9B, 1JFI, 1NVP, 4ROC, 4ROE, 4ROD, 5IY9, 5IYA, 5FUR, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6
Dynodwyr
Cyfenwau	TBP, GTF2D, GTF2D1, HDL4, SCA17, TFIID, TATA-box binding protein, TATA-binding protein, TBP1
Dynodwyr allanol	OMIM: 600075 HomoloGene: 2404 GeneCards: TBP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • transcription factor binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001948, GO:0016582 protein binding • enzyme binding • TFIIB-class transcription factor binding • aryl hydrocarbon receptor binding • GO:0001158 cis-regulatory region sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • RNA polymerase III general transcription initiation factor activity • GO:0000983 RNA polymerase II general transcription initiation factor activity • RNA polymerase II core promoter sequence-specific DNA binding • RNA polymerase III transcription regulatory region sequence-specific DNA binding Cydrannau o'r gell • cytoplasm • transcription factor TFIID complex • male pronucleus • female pronucleus • nucleoplasm • transcription factor TFIIA complex • pronucleus • cnewyllyn cell • transcription preinitiation complex • GO:0009327 protein-containing complex • transcription factor TFIIIB complex • transcription regulator complex Prosesau biolegol • termination of RNA polymerase I transcription • epigenetic maintenance of chromatin in transcription-competent conformation • GO:0009373 regulation of transcription, DNA-templated • transcription initiation from RNA polymerase I promoter • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • spermatogenesis • DNA-templated transcription, initiation • transcription initiation from RNA polymerase II promoter • snRNA transcription by RNA polymerase II • regulation of signal transduction by p53 class mediator • GO:0022415 viral process • regulation of transcription by RNA polymerase III • transcription by RNA polymerase II • transcription by RNA polymerase III • RNA polymerase II preinitiation complex assembly • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • RNA polymerase III preinitiation complex assembly • GO:0001183 transcription elongation from RNA polymerase I promoter Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6908	n/a
Ensembl	ENSG00000112592	n/a
UniProt	P20226	n/a
RefSeq (mRNA)	NM_003194 NM_001172085	n/a
RefSeq (protein)	NP_001165556 NP_003185	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TBP.

• HDL4
• GTF2D
• SCA17
• TFIID
• GTF2D1

Llyfryddiaeth

• "Doubly Spliced RNA of Hepatitis B Virus Suppresses Viral Transcription via TATA-Binding Protein and Induces Stress Granule Assembly. ". J Virol. 2015. PMID 26339052.
• "Multivalent engagement of TFIID to nucleosomes. ". PLoS One. 2013. PMID 24039962.
• "Human TFIID binds to core promoter DNA in a reorganized structural state. ". Cell. 2013. PMID 23332750.
• "TATA binding proteins can recognize nontraditional DNA sequences. ". Biophys J. 2012. PMID 23062343.
• "Severe and rapidly progressing cognitive phenotype in a SCA17-family with only marginally expanded CAG/CAA repeats in the TATA-box binding protein gene: a case report.". BMC Neurol. 2012. PMID 22889412.