TNFRSF12A

Protein sy'n cael ei godio yn y corff dynol gan y genyn TNFRSF12A yw TNFRSF12A a elwir hefyd yn Tumor necrosis factor receptor superfamily member 12A a TNF receptor superfamily member 12a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p13.3.

TNFRSF12A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2EQP, 2KMZ, 2RPJ
Dynodwyr
Cyfenwau	TNFRSF12A, CD266, FN14, TWEAKR, tumor necrosis factor receptor superfamily member 12A, TNF receptor superfamily member 12A
Dynodwyr allanol	OMIM: 605914 HomoloGene: 8451 GeneCards: TNFRSF12A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • ruffle • integral component of membrane • cell surface • Cellbilen • bilen Prosesau biolegol • GO:0097285 apoptotic process • substrate-dependent cell migration, cell attachment to substrate • multicellular organism development • positive regulation of extrinsic apoptotic signaling pathway • cell differentiation • positive regulation of axon extension • cell adhesion • tumor necrosis factor-mediated signaling pathway • regulation of wound healing • regulation of angiogenesis • extrinsic apoptotic signaling pathway • angiogenesis • positive regulation of apoptotic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51330	n/a
Ensembl	ENSG00000006327	n/a
UniProt	Q9NP84	n/a
RefSeq (mRNA)	NM_016639	n/a
RefSeq (protein)	NP_057723	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TNFRSF12A.

• FN14
• CD266
• TWEAKR

Llyfryddiaeth

• "Fibroblast Growth Factor-Inducible 14: Multiple Roles in Tumor Metastasis. ". Curr Mol Med. 2015. PMID 26592249.
• "Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors. ". Clin Cancer Res. 2016. PMID 26446946.
• "Fn14 hepatic progenitor cells are associated with liver fibrosis in biliary atresia. ". Pediatr Surg Int. 2017. PMID 28180936.
• "Knockdown of the differentially expressed gene TNFRSF12A inhibits hepatocellular carcinoma cell proliferation and migration in vitro. ". Mol Med Rep. 2017. PMID 28138696.
• "Effect of procyanidine on VEGFR-2 expression and transduction pathway in rat endothelial progenitor cells under high glucose conditions.". Genet Mol Res. 2016. PMID 27051016.