TNFRSF21

Protein sy'n cael ei godio yn y corff dynol gan y genyn TNFRSF21 yw TNFRSF21 a elwir hefyd yn TNF receptor superfamily member 21 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p12.3.

TNFRSF21
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3QO4, 3U3P, 3U3Q, 3U3S, 3U3T, 3U3V, 2DBH
Dynodwyr
Cyfenwau	TNFRSF21, BM-018, CD358, DR6, tumor necrosis factor receptor superfamily member 21, TNF receptor superfamily member 21
Dynodwyr allanol	OMIM: 605732 HomoloGene: 8696 GeneCards: TNFRSF21
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • tumor necrosis factor-activated receptor activity Cydrannau o'r gell • integral component of membrane • bilen • integral component of plasma membrane • axon • Cellbilen • intrinsic component of plasma membrane • cytoplasm Prosesau biolegol • regulation of apoptotic process • immune system process • cellular response to tumor necrosis factor • response to lipopolysaccharide • regulation of cell population proliferation • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • apoptotic signaling pathway • inflammatory response • negative regulation of myelination • GO:0072468 signal transduction • GO:0097285 apoptotic process • oligodendrocyte apoptotic process • negative regulation of B cell proliferation • neuron apoptotic process • humoral immune response • myelination • negative regulation of T cell proliferation • T cell receptor signaling pathway • tumor necrosis factor-mediated signaling pathway • B cell apoptotic process • adaptive immune response • regulation of oligodendrocyte differentiation • regulation of lipid metabolic process • axonal fasciculation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	27242	n/a
Ensembl	ENSG00000146072	n/a
UniProt	O75509	n/a
RefSeq (mRNA)	NM_014452	n/a
RefSeq (protein)	NP_055267	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TNFRSF21.

• DR6
• CD358
• BM-018

Llyfryddiaeth

• "S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS. ". Acta Crystallogr D Biol Crystallogr. 2012. PMID 22525750.
• "Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB. ". Oncogene. 2001. PMID 11753679.
• "Death receptor 6 is a novel plasmacytoid dendritic cell-specific receptor and modulates type I interferon production. ". Protein Cell. 2016. PMID 26906057.
• "Death receptor 6 is epigenetically silenced by histone deacetylation in endometriosis and promotes the pathogenesis of endometriosis. ". Am J Reprod Immunol. 2013. PMID 24028773.
• "DR6 as a diagnostic and predictive biomarker in adult sarcoma.". PLoS One. 2012. PMID 22567163.