TPT1

Protein sy'n cael ei godio yn y corff dynol gan y genyn TPT1 yw TPT1 a elwir hefyd yn Translationally-controlled tumor protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 13, band 13q14.13.

TPT1-AS1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1YZ1, 3EBM, 4Z9V, 2HR9
Dynodwyr
Cyfenwau	TPT1-AS1, HRF, TCTP, p02, p23, tumor protein, translationally-controlled 1, TPT1 antisense RNA 1
Dynodwyr allanol	OMIM: 600763 HomoloGene: 55730 GeneCards: TPT1-AS1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium ion binding • GO:0001948, GO:0016582 protein binding • microtubule binding • RNA binding Cydrannau o'r gell • cytoplasm • multivesicular body • tubulin complex • extracellular exosome • cnewyllyn cell • extracellular space • cytosol • spindle pole • cytoplasmic microtubule Prosesau biolegol • regulation of apoptotic process • response to virus • cellular calcium ion homeostasis • negative regulation of apoptotic process • negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage • calcium ion transport • cell differentiation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	100190939	n/a
Ensembl	ENSG00000170919	n/a
UniProt	P13693	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	NP_001273201 NP_001273202 NP_003286	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TPT1.

• HRF
• p02
• p23
• TCTP

Llyfryddiaeth

• "Expression of Translationally Controlled Tumor Protein in Human Kidney and in Renal Cell Carcinoma. ". Biomed Res Int. 2015. PMID 26425551.
• "RNA interference‑mediated knockdown of translationally controlled tumor protein induces apoptosis, and inhibits growth and invasion in glioma cells. ". Mol Med Rep. 2015. PMID 26328748.
• "Synergistic Actions of Histamine-Releasing Factor and Histamine Releasing Factor-Reactive IgE in Chronic Urticaria. ". Int Arch Allergy Immunol. 2017. PMID 28219065.
• "Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin. ". Cell Commun Signal. 2017. PMID 28143584.
• "Insights into the role and regulation of TCTP in skeletal muscle.". Oncotarget. 2017. PMID 27813490.