TRIO

Protein sy'n cael ei godio yn y corff dynol gan y genyn TRIO yw TRIO a elwir hefyd yn Triple functional domain protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5p15.2.

TRIO
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1NTY, 2NZ8
Dynodwyr
Cyfenwau	TRIO, ARHGEF23, tgat, trio Rho guanine nucleotide exchange factor, MEBAS, MRD44, MRD63, TRIO gene
Dynodwyr allanol	OMIM: 601893 HomoloGene: 20847 GeneCards: TRIO
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein kinase activity • guanyl-nucleotide exchange factor activity • kinase activity • protein serine/threonine kinase activity • GO:0001948, GO:0016582 protein binding • ATP binding Cydrannau o'r gell • cytoplasm • cytosol Prosesau biolegol • phosphorylation • protein phosphorylation • transmembrane receptor protein tyrosine phosphatase signaling pathway • positive regulation of apoptotic process • regulation of Rho protein signal transduction • regulation of small GTPase mediated signal transduction • negative regulation of fat cell differentiation • G protein-coupled receptor signaling pathway • axon guidance • central nervous system development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7204	n/a
Ensembl	ENSG00000038382	n/a
UniProt	O75962	n/a
RefSeq (mRNA)	NM_007118	n/a
RefSeq (protein)	NP_009049	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TRIO.

• tgat
• MEBAS
• MRD44
• ARHGEF23

Llyfryddiaeth

• TRIO-Related Intellectual Disability. 1993. PMID 28796471.
• "Upregulated TRIO expression correlates with a malignant phenotype in human hepatocellular carcinoma. ". Tumour Biol. 2015. PMID 25851347.
• "Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesis. ". Mol Biol Cell. 2014. PMID 25355950.
• "The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation. ". Mol Biol Cell. 2012. PMID 22696684.
• "Kalirin/Trio Rho guanine nucleotide exchange factors regulate a novel step in secretory granule maturation.". Mol Biol Cell. 2007. PMID 17881726.