TSN

Protein sy'n cael ei godio yn y corff dynol gan y genyn TSN yw TSN a elwir hefyd yn Translin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q14.3.

TSN
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1J1J, 3PJA, 3QB5, 4WYV
Dynodwyr
Cyfenwau	TSN, BCLF-1, C3PO, RCHF1, REHF-1, TBRBP, TRSLN, translin
Dynodwyr allanol	OMIM: 600575 HomoloGene: 3397 GeneCards: TSN
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • nuclease activity • endonuclease activity • sequence-specific DNA binding • GO:0001948, GO:0016582 protein binding • mRNA binding • hydrolase activity • RNA binding • single-stranded DNA binding • identical protein binding • endoribonuclease activity • GO:0032403 protein-containing complex binding Cydrannau o'r gell • cytoplasm • cytosol • cnewyllyn cell Prosesau biolegol • DNA recombination • nucleic acid phosphodiester bond hydrolysis • RNA metabolic process • RNA phosphodiester bond hydrolysis, endonucleolytic • GO:0070919 production of siRNA involved in RNA interference Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7247	n/a
Ensembl	ENSG00000211460	n/a
UniProt	Q15631	n/a
RefSeq (mRNA)	NM_001261401 NM_004622	n/a
RefSeq (protein)	NP_001248330 NP_004613	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TSN.

• C3PO
• RCHF1
• TBRBP
• TRSLN
• BCLF-1
• REHF-1

Llyfryddiaeth

• "The human protein translin specifically binds single-stranded microsatellite repeats, d(GT)n, and G-strand telomeric repeats, d(TTAGGG)n: a study of the binding parameters. ". J Mol Biol. 2004. PMID 15544804.
• "Structure of human translin at 2.2 A resolution. ". Acta Crystallogr D Biol Crystallogr. 2004. PMID 15039555.
• "A novel open-barrel structure of octameric translin reveals a potential RNA entryway. ". J Mol Biol. 2015. PMID 25433126.
• "Conformational transitions in human translin enable nucleic acid binding. ". Nucleic Acids Res. 2013. PMID 23980029.
• "Conformational changes induced in the human protein translin and in the single-stranded oligodeoxynucleotides d(GT)(12) and d(TTAGGG)(5) upon binding of these oligodeoxynucleotides by translin.". J Biomol Struct Dyn. 2005. PMID 16218753.