UBTF

Protein sy'n cael ei godio yn y corff dynol gan y genyn UBTF yw UBTF a elwir hefyd yn Upstream binding transcription factor, RNA polymerase I (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q21.31.

UBTF
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1K99, 1L8Y, 1L8Z, 2HDZ
Dynodwyr
Cyfenwau	UBTF, NOR-90, UBF, UBF-1, UBF1, UBF2, upstream binding transcription factor, RNA polymerase I, CONDBA, upstream binding transcription factor
Dynodwyr allanol	OMIM: 600673 HomoloGene: 7970 GeneCards: UBTF
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0001187 RNA polymerase I core promoter sequence-specific DNA binding • RNA polymerase I cis-regulatory region sequence-specific DNA binding • GO:0001948, GO:0016582 protein binding • chromatin binding • RNA binding • scaffold protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • nucleolus • cnewyllyn cell • nucleoplasm • fibrillar center Prosesau biolegol • transcription initiation from RNA polymerase I promoter • transcription by RNA polymerase I • termination of RNA polymerase I transcription • positive regulation of transcription by RNA polymerase I • GO:0001183 transcription elongation from RNA polymerase I promoter • regulation of glucose mediated signaling pathway • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • regulation of transcription by RNA polymerase I • RNA polymerase I preinitiation complex assembly • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7343	n/a
Ensembl	ENSG00000108312	n/a
UniProt	P17480	n/a
RefSeq (mRNA)	NM_001076683 NM_001076684 NM_014233	n/a
RefSeq (protein)	NP_001070151 NP_001070152 NP_055048	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UBTF.

• UBF
• UBF1
• UBF2
• UBF-1
• CONDBA
• NOR-90

Llyfryddiaeth

• "Involvement of phosphatidylinositol 4,5-bisphosphate in RNA polymerase I transcription. ". J Cell Sci. 2013. PMID 23591814.
• "[Expression profiling of UBF, a novel member of UBC family]. ". Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2004. PMID 21162312.
• "Internal Associations of the Acidic Region of Upstream Binding Factor Control Its Nucleolar Localization. ". Mol Cell Biol. 2017. PMID 28874518.
• "Heterozygous De Novo UBTF Gain-of-Function Variant Is Associated with Neurodegeneration in Childhood. ". Am J Hum Genet. 2017. PMID 28777933.
• "Upstream binding factor inhibits herpes simplex virus replication.". Virology. 2015. PMID 25965800.