VPS25

Protein sy'n cael ei godio yn y corff dynol gan y genyn VPS25 yw VPS25 a elwir hefyd yn Vacuolar protein sorting 25 (Yeast), isoform CRA_a a Vacuolar protein sorting 25 homolog (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q21.2.

VPS25
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2ZME, 3CUQ, 3HTU
Dynodwyr
Cyfenwau	VPS25, DERP9, EAP20, FAP20, vacuolar protein sorting 25 homolog
Dynodwyr allanol	OMIM: 610907 HomoloGene: 6303 GeneCards: VPS25
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • protein N-terminus binding • structural molecule activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • cytosol • endosome • bilen • nucleoplasm • endosome membrane • extracellular exosome • cnewyllyn cell • ESCRT II complex Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • multivesicular body assembly • transcription, DNA-templated • endosomal transport • protein transport • protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway • macroautophagy • negative regulation of epidermal growth factor-activated receptor activity • GO:0015915 transport • multivesicular body sorting pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	84313	n/a
Ensembl	ENSG00000131475	n/a
UniProt	Q9BRG1	n/a
RefSeq (mRNA)	NM_032353	n/a
RefSeq (protein)	NP_115729 NP_115729.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn VPS25.

• DERP9
• EAP20
• FAP20

Llyfryddiaeth

• "Integrated structural model and membrane targeting mechanism of the human ESCRT-II complex. ". Dev Cell. 2008. PMID 18539118.
• "Evidence that the endosomal sorting complex required for transport-II (ESCRT-II) is required for efficient human immunodeficiency virus-1 (HIV-1) production. ". Retrovirology. 2015. PMID 26268989.
• "Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis. ". Dev Cell. 2009. PMID 19686684.
• "Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes. ". J Cell Biol. 2004. PMID 15007060.
• "Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting.". Biochem J. 2005. PMID 15511219.